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10.1016/j.virusres.2020.198148

http://scihub22266oqcxt.onion/10.1016/j.virusres.2020.198148
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32866536!7455115!32866536
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suck abstract from ncbi


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pmid32866536      Virus+Res 2020 ; 289 (ä): 198148
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  • Association of vitamin D with the modulation of the disease severity in COVID-19 #MMPMID32866536
  • Mardani R; Alamdary A; Mousavi Nasab SD; Gholami R; Ahmadi N; Gholami A
  • Virus Res 2020[Nov]; 289 (ä): 198148 PMID32866536show ga
  • In late 2019, SARS-CoV-2 started to spread throughout the world causing the COVID-19 that has taken a considerable number of lives. Results obtained from several investigations have explained the virus origin, pathogenicity, and transmission. Similar to SARS coronavirus, the pulmonary angiotensin converting enzyme (ACE) 2 was introduced as the virus receptor for entering the cell. An increased body of epidemiological and clinical evidences has shown modulating effects of vitamin D in lung injuries through several mechanisms. Several clinical symptoms as well as molecular factors have shown to be related to the disease transmission and severity. In this study, vitamin D, ACE concentrations, and neutrophil to lymphocyte ratio (NLR) were measured in patients with confirmed COVID-19 in comparison with control group. Results demonstrated significant alterations in vitamin D and ACE levels as well as NLR in the patients' group. Contribution of those factors with the prognosis and severity of the disease has been shown.
  • |*Betacoronavirus[MESH]
  • |*Pandemics[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/blood/*complications[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Leukocyte Count[MESH]
  • |Lymphocyte Count[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neutrophils[MESH]
  • |Peptidyl-Dipeptidase A/blood[MESH]
  • |Pneumonia, Viral/blood/*complications[MESH]
  • |SARS-CoV-2[MESH]
  • |Vitamin D Deficiency/*complications[MESH]
  • |Vitamin D/blood/*physiology[MESH]


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  • suck abstract from ncbi

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