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10.7774/cevr.2020.9.2.169 http://scihub22266oqcxt.onion/10.7774/cevr.2020.9.2.169 32864374!7445319!32864374     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Exp+Vaccine+Res 2020 ; 9 (2): 169-173 Nephropedia Template TP {{tp|p=32864374|t=2020. Coronavirus epitope prediction from highly conserved region of spike protein |pdf=|usr=}}{{32864374}} gab.com Text Coronavirus epitope prediction from highly conserved region of spike protein JO: Clin Exp Vaccine Res http://www.kidney.de/pget.php?&tw=1&pmid=32864374 #FOAvip PURPOSE: The aim of this research was to predict the epitope for coronavirus family spike protein. Coronavirus family is highly evolved viruses which cause several outbreaks in the past decades. Therefore, it is crucial to design a global vaccine candidate to prevent the coronavirus outbreak in the future. MATERIALS AND METHODS: The spike protein amino acid sequences from nine coronavirus family were searched in the Uniprot database. The spike protein sequences were aligned using Clustal method. The highly conservatives amino acids were analyzed its B cell linear and continuous epitopes and T cell epitopes. RESULTS: From the alignment results it was found that there is a highly conserved region in the extracellular domain of spike protein. With prediction methods from this highly conserved region, B cell and T cell epitopes from spike protein were derived. CONCLUSION: From several different prediction results, B cell epitope and T cell epitope were identified in the highly conserved region thus it is promising to be developed as a coronavirus vaccine candidate. Twit Text FOAVip Coronavirus epitope prediction from highly conserved region of spike protein ????Clin Exp Vaccine Res http://www.kidney.de/pget.php?&tw=1&pmid=32864374 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32864374 #FOAvip English Wikipedia <ref>{{Cite pmid|32864374}}</ref> Coronavirus epitope prediction from highly conserved region of spike protein #MMPMID32864374 Yurina V Clin Exp Vaccine Res 2020[Jul]; 9 (2): 169-173 PMID32864374show ga PURPOSE: The aim of this research was to predict the epitope for coronavirus family spike protein. Coronavirus family is highly evolved viruses which cause several outbreaks in the past decades. Therefore, it is crucial to design a global vaccine candidate to prevent the coronavirus outbreak in the future. MATERIALS AND METHODS: The spike protein amino acid sequences from nine coronavirus family were searched in the Uniprot database. The spike protein sequences were aligned using Clustal method. The highly conservatives amino acids were analyzed its B cell linear and continuous epitopes and T cell epitopes. RESULTS: From the alignment results it was found that there is a highly conserved region in the extracellular domain of spike protein. With prediction methods from this highly conserved region, B cell and T cell epitopes from spike protein were derived. CONCLUSION: From several different prediction results, B cell epitope and T cell epitope were identified in the highly conserved region thus it is promising to be developed as a coronavirus vaccine candidate. äCoronavirus epitope prediction from highly conserved region of spike p(epmc).pdf DeepDyve Pubget Overpricing