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10.1177/1591019920954603

http://scihub22266oqcxt.onion/10.1177/1591019920954603
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32862753!7586005!32862753
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suck abstract from ncbi

pmid32862753      Interv+Neuroradiol 2020 ; 26 (5): 623-628
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  • Predictors of mortality for patients with COVID-19 and large vessel occlusion #MMPMID32862753
  • Altschul DJ; Esenwa C; Haranhalli N; Unda SR; de La Garza Ramos R; Dardick J; Fernandez-Torres J; Toma A; Labovitz D; Cheng N; Lee SK; Brook A; Zampolin R
  • Interv Neuroradiol 2020[Oct]; 26 (5): 623-628 PMID32862753show ga
  • BACKGROUND: This study evaluates the mortality risk of patients with emergent large vessel occlusion (ELVO) and COVID-19 during the pandemic. METHODS: We performed a retrospective cohort study of two cohorts of consecutive patients with ELVO admitted to a quaternary hospital from March 1 to April 17, 2020. We abstracted data from electronic health records on baseline, biomarker profiles, key time points, quality measures and radiographic data. RESULTS: Of 179 patients admitted with ischemic stroke, 36 had ELVO. Patients with COVID-19 and ELVO had a higher risk of mortality during the pandemic versus patients without COVID-19 (OR 16.63, p = 0.004). An age-based sub-analysis showed in-hospital mortality in 60% of COVID-19 positive patients between 61-70 years-old, 66.7% in between 51-60 years-old, 50% in between 41-50 years-old and 33.3% in between 31-40 years old. Patients that presented with pulmonary symptoms at time of stroke presentation had 71.4% mortality rate. 27.3% of COVID-19 patients presenting with ELVO had a good outcome at discharge (mRS 0-2). Patients with a history of cigarette smoking (p = 0.003), elevated d-dimer (p = 0.007), failure to recanalize (p = 0.007), and elevated ferritin levels (p = 0.006) had an increased risk of mortality. CONCLUSION: Patients with COVID-19 and ELVO had a significantly higher risk for mortality compared to COVID-19 negative patients with ELVO. A small percentage of COVID-19 ELVO patients had good outcomes. Age greater than 60 and pulmonary symptoms at presentation have higher risk for mortality. Other risk factors for mortality were a history of cigarette smoking, elevated, failure to recanalize, elevated d-dimer and ferritin levels.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Arterial Occlusive Diseases/*mortality[MESH]
  • |COVID-19[MESH]
  • |Cohort Studies[MESH]
  • |Coronavirus Infections/*complications/*mortality[MESH]
  • |Female[MESH]
  • |Ferritins/blood[MESH]
  • |Fibrin Fibrinogen Degradation Products/analysis[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Lung Diseases/etiology/mortality[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/*mortality[MESH]
  • |Predictive Value of Tests[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Assessment[MESH]
  • |Risk Factors[MESH]
  • |Smoking/mortality[MESH]
  • |Stroke/etiology/mortality[MESH]


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