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10.1016/j.dsx.2020.08.014

http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.08.014
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32862098!7439970!32862098
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suck abstract from ncbi

pmid32862098      Diabetes+Metab+Syndr 2020 ; 14 (6): 1595-1602
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  • Burden of diabetes mellitus and its impact on COVID-19 patients: A meta-analysis of real-world evidence #MMPMID32862098
  • Hussain S; Baxi H; Chand Jamali M; Nisar N; Hussain MS
  • Diabetes Metab Syndr 2020[Nov]; 14 (6): 1595-1602 PMID32862098show ga
  • BACKGROUND & AIMS: Coronavirus disease 2019 (COVID-19) spreads rapidly and within no time, it has been declared a pandemic by the World Health Organization. Evidence suggests diabetes to be a risk factor for the progression and poor prognosis of COVID-19. Therefore, we aimed to understand the pooled prevalence of diabetes in patients infected with COVID-19. We also aimed to compute the risk of mortality and ICU admissions in COVID-19 patients with and without diabetes. METHODS: A comprehensive literature search was performed in PubMed to identify the articles reporting the diabetes prevalence and risk of mortality or ICU admission in COVID-19 patients. The primary outcome was to compute the pooled prevalence of diabetes in COVID-19 patients. Secondary outcomes included risk of mortality and ICU admissions in COVID-19 patients with diabetes compared to patients without diabetes. RESULTS: This meta-analysis was based on a total of 23007 patients from 43 studies. The pooled prevalence of diabetes in patients infected with COVID-19 was found to be 15% (95% CI: 12%-18%), p = <0.0001. Mortality risk was found to be significantly higher in COVID-19 patients with diabetes as compared to COVID-19 patients without diabetes with a pooled risk ratio of 1.61 (95% CI: 1.16-2.25%), p = 0.005. Likewise, risk of ICU admission rate was significantly higher in COVID-19 patients with diabetes as compared to COVID-19 patients without diabetes with a pooled risk ratio of 1.88 (1.20%-2.93%), p = 0.006. CONCLUSION: This meta-analysis found a high prevalence of diabetes and higher mortality and ICU admission risk in COVID-19 patients with diabetes.
  • |*Cost of Illness[MESH]
  • |*Pragmatic Clinical Trials as Topic/methods[MESH]
  • |COVID-19/diagnosis/*mortality[MESH]
  • |Diabetes Mellitus/diagnosis/*mortality[MESH]
  • |Hospitalization/trends[MESH]
  • |Humans[MESH]
  • |Intensive Care Units/trends[MESH]


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