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10.1093/femspd/ftaa046 http://scihub22266oqcxt.onion/10.1093/femspd/ftaa046 32860686!7499567!32860686     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32860686&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pathog+Dis 2020 ; 78 (7): ä Nephropedia Template TP {{tp|p=32860686|t=2020. The past, present and future of RNA respiratory viruses: influenza and coronaviruses |pdf=|usr=}}{{32860686}} gab.com Text The past, present and future of RNA respiratory viruses: influenza and coronaviruses JO: Pathog Dis http://www.kidney.de/pget.php?&tw=1&pmid=32860686 #FOAvip Influenza virus and coronaviruses continue to cause pandemics across the globe. We now have a greater understanding of their functions. Unfortunately, the number of drugs in our armory to defend us against them is inadequate. This may require us to think about what mechanisms to address. Here, we review the biological properties of these viruses, their genetic evolution and antiviral therapies that can be used or have been attempted. We will describe several classes of drugs such as serine protease inhibitors, heparin, heparan sulfate receptor inhibitors, chelating agents, immunomodulators and many others. We also briefly describe some of the drug repurposing efforts that have taken place in an effort to rapidly identify molecules to treat patients with COVID-19. While we put a heavy emphasis on the past and present efforts, we also provide some thoughts about what we need to do to prepare for respiratory viral threats in the future. Twit Text FOAVip The past, present and future of RNA respiratory viruses: influenza and coronaviruses ????Pathog Dis http://www.kidney.de/pget.php?&tw=1&pmid=32860686 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32860686 #FOAvip English Wikipedia <ref>{{Cite pmid|32860686}}</ref> The past, present and future of RNA respiratory viruses: influenza and coronaviruses #MMPMID32860686 Makarov V; Riabova O; Ekins S; Pluzhnikov N; Chepur S Pathog Dis 2020[Oct]; 78 (7): ä PMID32860686show ga Influenza virus and coronaviruses continue to cause pandemics across the globe. We now have a greater understanding of their functions. Unfortunately, the number of drugs in our armory to defend us against them is inadequate. This may require us to think about what mechanisms to address. Here, we review the biological properties of these viruses, their genetic evolution and antiviral therapies that can be used or have been attempted. We will describe several classes of drugs such as serine protease inhibitors, heparin, heparan sulfate receptor inhibitors, chelating agents, immunomodulators and many others. We also briefly describe some of the drug repurposing efforts that have taken place in an effort to rapidly identify molecules to treat patients with COVID-19. While we put a heavy emphasis on the past and present efforts, we also provide some thoughts about what we need to do to prepare for respiratory viral threats in the future. |*Drug Repositioning[MESH] |*Pandemics[MESH] |Anticoagulants/therapeutic use[MESH] |Antimalarials/therapeutic use[MESH] |Antioxidants/therapeutic use[MESH] |Antiviral Agents/*therapeutic use[MESH] |Chelating Agents/therapeutic use[MESH] |Coronavirus Infections/drug therapy/*epidemiology/virology[MESH] |Coronavirus/*drug effects/genetics/growth & development/pathogenicity[MESH] |Glycoconjugates/therapeutic use[MESH] |Humans[MESH] |Immunologic Factors/therapeutic use[MESH] |Influenza, Human/drug therapy/*epidemiology/virology[MESH] |Orthomyxoviridae/*drug effects/genetics/growth & development/pathogenicity[MESH]The past, present and future of RNA respiratory viruses: influenza and(epmc).pdf DeepDyve Pubget Overpricing