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10.1016/j.blre.2020.100742

http://scihub22266oqcxt.onion/10.1016/j.blre.2020.100742
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suck abstract from ncbi


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pmid32854985      Blood+Rev 2021 ; 46 (ä): 100742
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  • Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome? #MMPMID32854985
  • Hamdan H; Hashmi SK; Lazarus H; Gale RP; Qu W; El Fakih R
  • Blood Rev 2021[Mar]; 46 (ä): 100742 PMID32854985show ga
  • Mesenchymal stromal cells (MSC) have immune regulatory and tissue regenerative properties. MSCs are being studied as a therapy option for many inflammatory and immune disorders and are approved to treat acute graft-versus-host disease (GvHD). The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic and associated coronavirus infectious disease-19 (COVID-19) has claimed many lives. Innovative therapies are needed. Preliminary data using MSCs in the setting of acute respiratory distress syndrome (ARDS) in COVID-19 are emerging. We review mechanisms of action of MSCs in inflammatory and immune conditions and discuss a potential role in persons with COVID-19.
  • |Animals[MESH]
  • |COVID-19/*therapy[MESH]
  • |Humans[MESH]
  • |Mesenchymal Stem Cell Transplantation/*methods[MESH]
  • |Respiratory Distress Syndrome/*therapy[MESH]


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