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10.1016/j.jinf.2020.08.036 http://scihub22266oqcxt.onion/10.1016/j.jinf.2020.08.036 32853599!7445469!32853599     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Infect 2021 ; 82 (2): 282-327 Nephropedia Template TP {{tp|p=32853599|t=2021. COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity |pdf=|usr=}}{{32853599}} gab.com Text COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity JO: J Infect http://www.kidney.de/pget.php?&tw=1&pmid=32853599 #FOAvip Adaptive Immune responses generated by SARS-CoV-2 virus in convalescent patients according to disease severity remain poorly characterized. To this end, we designed a prospective study (NCT04365322) that included 60 COVID-19 convalescent patients (1-month post infection) in two cohorts respectively entitled mild illness and severe pneumonia. The monitoring of peripheral immune responses was performed using IFN? ELISpot assay. The serology index of each patient was investigated at the same time. Patients with severe pneumonia were older and had more comorbidities than patients with mild illness. T-cell responses in term of frequency and intensity were clearly distinct between mild illness and severe pneumonia patients. Furthermore, our results demonstrated that recent history of COVID-19 did not hamper viral memory T-cell pool against common viruses (Cytomegalovirus, Epstein-Barr-virus and Flu-virus). The presence of potent adaptive immunity even in patients who underwent severe pneumonia sustain the rationale for the development of protective therapeutics against SARS-CoV-2. Twit Text FOAVip COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity ????J Infect http://www.kidney.de/pget.php?&tw=1&pmid=32853599 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32853599 #FOAvip English Wikipedia <ref>{{Cite pmid|32853599}}</ref> COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity #MMPMID32853599 Kroemer M; Spehner L; Vettoretti L; Bouard A; Eberst G; Pili Floury S; Capellier G; Lepiller Q; Orillard E; Mansi L; Clairet AL; Westeel V; Limat S; Dubois M; Malinowski L; Bohard L; Borg C; Chirouze C; Bouiller K J Infect 2021[Feb]; 82 (2): 282-327 PMID32853599show ga Adaptive Immune responses generated by SARS-CoV-2 virus in convalescent patients according to disease severity remain poorly characterized. To this end, we designed a prospective study (NCT04365322) that included 60 COVID-19 convalescent patients (1-month post infection) in two cohorts respectively entitled mild illness and severe pneumonia. The monitoring of peripheral immune responses was performed using IFN? ELISpot assay. The serology index of each patient was investigated at the same time. Patients with severe pneumonia were older and had more comorbidities than patients with mild illness. T-cell responses in term of frequency and intensity were clearly distinct between mild illness and severe pneumonia patients. Furthermore, our results demonstrated that recent history of COVID-19 did not hamper viral memory T-cell pool against common viruses (Cytomegalovirus, Epstein-Barr-virus and Flu-virus). The presence of potent adaptive immunity even in patients who underwent severe pneumonia sustain the rationale for the development of protective therapeutics against SARS-CoV-2. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |China[MESH] |Humans[MESH] |Immunity, Cellular[MESH] |Prospective Studies[MESH] |Retrospective Studies[MESH] |Severity of Illness Index[MESH]COVID-19 patients display distinct SARS-CoV-2 specific T-cell response(epmc).pdf DeepDyve Pubget Overpricing