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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Future+Microbiol 2020 ; 15 (ä): 1287-1305 Nephropedia Template TP
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Pathogenesis, clinical manifestations and complications of coronavirus disease 2019 (COVID-19) #MMPMID32851877
Kordzadeh-Kermani E; Khalili H; Karimzadeh I
Future Microbiol 2020[Sep]; 15 (ä): 1287-1305 PMID32851877show ga
Aim: Despite the similarities in the pathogenesis of the beta coronaviruses, the precise infective mechanisms of SARS-CoV-2 remain unclear. Objective: In this review, we aim to focus on the proposed theories behind the pathogenesis of SARS-CoV-2 and highlight the clinical complications related to COVID-19. Methods: We conducted a literature search in Pubmed, Scopus and Google Scholar for the relevant articles regarding clinical complications and pathogenesis of COVID-19. Results: Related articles were included and discussed. Conclusion: Respiratory system and the lungs are the most commonly involved sites of COVID-19 infection. Cardiovascular, liver, kidneys, gastrointestinal and central nervous systems are involved with different frequencies and degrees of severity.