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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Thorax 2020 ; 75 (12): 1116-1118 Nephropedia Template TP
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Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients #MMPMID32839288
Recalde-Zamacona B; Garcia-Tobar L; Argueta A; Alvarez L; De Andrea CE; Fernandez Alonso M; Ezponda A; Carmona Torre F; Jordan Iborra C; Quiroga JA; Del Pozo JL; Zulueta JJ; Echarri G; Landecho MF; Lozano MD
Thorax 2020[Dec]; 75 (12): 1116-1118 PMID32839288show ga
In December 2019, an outbreak of severe acute respiratory syndrome associated to SARS-CoV2 was reported in Wuhan, China. To date, little is known on histopathological findings in patients infected with the new SARS-CoV2. Lung histopathology shows features of acute and organising diffuse alveolar damage. Subtle cellular inflammatory infiltrate has been found in line with the cytokine storm theory. Medium-size vessel thrombi were frequent, but capillary thrombi were not present. Despite the elevation of biochemical markers of cardiac injury, little histopathological damage could be confirmed. Viral RNA from paraffin sections was detected at least in one organ in 90% patients.