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10.1016/j.medj.2020.05.002 http://scihub22266oqcxt.onion/10.1016/j.medj.2020.05.002 32838352!7235581!32838352     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32838352&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Med 2020 ; 1 (1): 128-138.e3 Nephropedia Template TP {{tp|p=32838352|t=2020. Validation of Predictors of Disease Severity and Outcomes in COVID-19 Patients: A Descriptive and Retrospective Study |pdf=|usr=}}{{32838352}} gab.com Text Validation of Predictors of Disease Severity and Outcomes in COVID-19 Patients: A Descriptive and Retrospective Study JO: Med http://www.kidney.de/pget.php?&tw=1&pmid=32838352 #FOAvip BACKGROUND: The severity and outcome of COVID-19 cases has been associated with the percentage of circulating lymphocytes (LYM%), levels of C-reactive protein (CRP), interleukin-6 (IL-6), procalcitonin (PCT), lactic acid (LA), and viral load (ORF1ab Ct). However, the predictive power of each of these indicators in disease classification and prognosis remains largely unclear. METHODS: We retrospectively collected information on the above parameters in 142 patients with COVID-19, stratifying them by survival or disease severity. FINDINGS: CRP, PCT, IL-6, LYM%, and ORF1ab Ct were significantly altered between survivors and non-survivors. LYM%, CRP, and IL-6 were the most sensitive and reliable factors in distinguishing between survivors and non-survivors. These indicators were significantly different between critically ill and severe/moderate patients. Only LYM% levels were significantly different between severe and moderate types. Among all the investigated indicators, LYM% was the most sensitive and reliable in discriminating between critically ill, severe, and moderate types and between survivors and non-survivors. CONCLUSIONS: CRP, PCT, IL-6, LYM%, and ORF1ab Ct, but not LA, could predict prognosis and guide classification of COVID-19 patients. LYM% was the most sensitive and reliable predictor for disease typing and prognosis. We recommend that LYM% be further investigated in the management of COVID-19. FUNDING: This study was supported in part by awards from the National Natural Science Foundation of China, the Foundation and Frontier Research Project of Chongqing, and the Chongqing Youth Top Talent Project. Twit Text FOAVip Validation of Predictors of Disease Severity and Outcomes in COVID-19 Patients: A Descriptive and Retrospective Study ????Med http://www.kidney.de/pget.php?&tw=1&pmid=32838352 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32838352 #FOAvip English Wikipedia <ref>{{Cite pmid|32838352}}</ref> Validation of Predictors of Disease Severity and Outcomes in COVID-19 Patients: A Descriptive and Retrospective Study #MMPMID32838352 Tan L; Kang X; Ji X; Li G; Wang Q; Li Y; Wang Q; Miao H Med 2020[Dec]; 1 (1): 128-138.e3 PMID32838352show ga BACKGROUND: The severity and outcome of COVID-19 cases has been associated with the percentage of circulating lymphocytes (LYM%), levels of C-reactive protein (CRP), interleukin-6 (IL-6), procalcitonin (PCT), lactic acid (LA), and viral load (ORF1ab Ct). However, the predictive power of each of these indicators in disease classification and prognosis remains largely unclear. METHODS: We retrospectively collected information on the above parameters in 142 patients with COVID-19, stratifying them by survival or disease severity. FINDINGS: CRP, PCT, IL-6, LYM%, and ORF1ab Ct were significantly altered between survivors and non-survivors. LYM%, CRP, and IL-6 were the most sensitive and reliable factors in distinguishing between survivors and non-survivors. These indicators were significantly different between critically ill and severe/moderate patients. Only LYM% levels were significantly different between severe and moderate types. Among all the investigated indicators, LYM% was the most sensitive and reliable in discriminating between critically ill, severe, and moderate types and between survivors and non-survivors. CONCLUSIONS: CRP, PCT, IL-6, LYM%, and ORF1ab Ct, but not LA, could predict prognosis and guide classification of COVID-19 patients. LYM% was the most sensitive and reliable predictor for disease typing and prognosis. We recommend that LYM% be further investigated in the management of COVID-19. FUNDING: This study was supported in part by awards from the National Natural Science Foundation of China, the Foundation and Frontier Research Project of Chongqing, and the Chongqing Youth Top Talent Project. |*COVID-19[MESH] |Adolescent[MESH] |C-Reactive Protein/analysis[MESH] |Critical Illness[MESH] |Humans[MESH] |Interleukin-6[MESH] |Procalcitonin[MESH] |Retrospective Studies[MESH] |SARS-CoV-2[MESH]Validation of Predictors of Disease Severity and Outcomes in COVID-19 (epmc).pdf DeepDyve Pubget Overpricing