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10.1016/j.xcrm.2020.100073 http://scihub22266oqcxt.onion/10.1016/j.xcrm.2020.100073 32838341!7405881!32838341     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32838341&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Cell+Rep+Med 2020 ; 1 (5): 100073 Nephropedia Template TP {{tp|p=32838341|t=2020. Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study |pdf=|usr=}}{{32838341}} gab.com Text Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study JO: Cell Rep Med http://www.kidney.de/pget.php?&tw=1&pmid=32838341 #FOAvip Bacille Calmette-Guerin (BCG) induces long-term boosting of innate immunity, termed trained immunity, and decreases susceptibility to respiratory tract infections. BCG vaccination trials for reducing SARS-CoV-2 infection are underway, but concerns have been raised regarding the potential harm of strong innate immune responses. To investigate the safety of BCG vaccination, we retrospectively assessed coronavirus disease 2019 (COVID-19) and related symptoms in three cohorts of healthy volunteers who either received BCG in the last 5 years or did not. BCG vaccination is not associated with increased incidence of symptoms during the COVID-19 outbreak in the Netherlands. Our data suggest that BCG vaccination might be associated with a decrease in the incidence of sickness during the COVID-19 pandemic (adjusted odds ratio [AOR] 0.58, p < 0.05), and lower incidence of extreme fatigue. In conclusion, recent BCG vaccination is safe, and large randomized trials are needed to reveal if BCG reduces the incidence and/or severity of SARS-CoV-2 infection. Twit Text FOAVip Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study ????Cell Rep Med http://www.kidney.de/pget.php?&tw=1&pmid=32838341 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32838341 #FOAvip English Wikipedia <ref>{{Cite pmid|32838341}}</ref> Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study #MMPMID32838341 Moorlag SJCFM; van Deuren RC; van Werkhoven CH; Jaeger M; Debisarun P; Taks E; Mourits VP; Koeken VACM; de Bree LCJ; Ten Doesschate T; Cleophas MC; Smeekens S; Oosting M; van de Veerdonk FL; Joosten LAB; Ten Oever J; van der Meer JWM; Curtis N; Aaby P; Stabell-Benn C; Giamarellos-Bourboulis EJ; Bonten M; van Crevel R; Netea MG Cell Rep Med 2020[Aug]; 1 (5): 100073 PMID32838341show ga Bacille Calmette-Guerin (BCG) induces long-term boosting of innate immunity, termed trained immunity, and decreases susceptibility to respiratory tract infections. BCG vaccination trials for reducing SARS-CoV-2 infection are underway, but concerns have been raised regarding the potential harm of strong innate immune responses. To investigate the safety of BCG vaccination, we retrospectively assessed coronavirus disease 2019 (COVID-19) and related symptoms in three cohorts of healthy volunteers who either received BCG in the last 5 years or did not. BCG vaccination is not associated with increased incidence of symptoms during the COVID-19 outbreak in the Netherlands. Our data suggest that BCG vaccination might be associated with a decrease in the incidence of sickness during the COVID-19 pandemic (adjusted odds ratio [AOR] 0.58, p < 0.05), and lower incidence of extreme fatigue. In conclusion, recent BCG vaccination is safe, and large randomized trials are needed to reveal if BCG reduces the incidence and/or severity of SARS-CoV-2 infection. |Adult[MESH] |Aged[MESH] |BCG Vaccine/*administration & dosage/immunology[MESH] |COVID-19/*epidemiology/immunology[MESH] |Female[MESH] |Humans[MESH] |Immunologic Memory[MESH] |Incidence[MESH] |Male[MESH] |Middle Aged[MESH] |Netherlands/epidemiology[MESH] |Retrospective Studies[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |Vaccination/*statistics & numerical data[MESH]Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with B(epmc).pdf DeepDyve Pubget Overpricing