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10.1016/j.yclnex.2020.07.003

http://scihub22266oqcxt.onion/10.1016/j.yclnex.2020.07.003
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32835086!7387270!32835086
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suck abstract from ncbi


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pmid32835086      Clin+Nutr+Exp 2020 ; 33 (ä): 24-31
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  • Effect of oral l-Glutamine supplementation on Covid-19 treatment #MMPMID32835086
  • Cengiz M; Borku Uysal B; Ikitimur H; Ozcan E; Islamoglu MS; Aktepe E; Yavuzer H; Yavuzer S
  • Clin Nutr Exp 2020[Oct]; 33 (ä): 24-31 PMID32835086show ga
  • OBJECTIVES: The aim of this study is to investigate the effect of oral l-Glutamine supplementation on hospitalization time, need for intensive care unit and Coronavirus Disease-19 (Covid-19) mortality. METHODS: The study included 30 Covid-19 patients using l-Glutamine and 30 Covid-19 patients who did not use l-Glutamine with similar age, gender and clinical status. Diagnostic tests, laboratory examinations, clinical findings and computed thorax tomography imaging of the patients were evaluated. RESULTS: Hospitalization time was 10.4 +/- 1.9 days in Covid-19 without L-Glutamine group and 8.9 +/- 1.8 days in Covid-19 with L-Glutamine group (p = 0.005). In Covid-19 without the L-Glutamine group, four patients require the ICU though no one in the other group required that (p = 0.038). Only one mortality was observed in Covid-19 without the L-Glutamine group (p = 0.999). CONCLUSIONS: Nutritional supplements such as L-Glutamine boost immune system especially by inhibition of inflammatory responses. Our results suggest adding enteral L-glutamine to the normal nutrition in the early period of Covid-19 infection may lead to a shortened hospital stay and lead to less need for ICU. Larger-scale studies are needed to evaluate the effect of adding enteral L-Glutamine to the currently used treatments in the infectious diseases especially like Covid-19.
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