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10.1186/s41232-020-00131-w

http://scihub22266oqcxt.onion/10.1186/s41232-020-00131-w
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32834892!7406680!32834892
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suck abstract from ncbi

pmid32834892      Inflamm+Regen 2020 ; 40 (ä): 19
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  • Macrophage activation syndrome and COVID-19 #MMPMID32834892
  • Otsuka R; Seino KI
  • Inflamm Regen 2020[]; 40 (ä): 19 PMID32834892show ga
  • An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the end of this life-threatening infectious disease is still unclear. Severe COVID-19 is often associated with hypercytokinemia, which is typically found in macrophage activation syndrome. SARS-CoV-2 infection causes this strong inflammation within the lung and propagates to respiratory and, ultimately, systemic organ malfunction. Although we have not fully understood the physiological and pathological aspects of COVID-19, current research progress indicates the effectiveness of anti-cytokine therapy. Here, we summarize macrophage activation syndrome and its possible contribution to COVID-19, and cytokine targeted attempts in severe COVID-19 cases.
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