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10.1016/j.jhin.2020.08.014

http://scihub22266oqcxt.onion/10.1016/j.jhin.2020.08.014
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32828864!7441047!32828864
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suck abstract from ncbi


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pmid32828864      J+Hosp+Infect 2020 ; 106 (3): 570-576
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  • Environmental contamination in the isolation rooms of COVID-19 patients with severe pneumonia requiring mechanical ventilation or high-flow oxygen therapy #MMPMID32828864
  • Ahn JY; An S; Sohn Y; Cho Y; Hyun JH; Baek YJ; Kim MH; Jeong SJ; Kim JH; Ku NS; Yeom JS; Smith DM; Lee H; Yong D; Lee YJ; Kim JW; Kim HR; Hwang J; Choi JY
  • J Hosp Infect 2020[Nov]; 106 (3): 570-576 PMID32828864show ga
  • BACKGROUND: Identifying the extent of environmental contamination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for infection control and prevention. The extent of environmental contamination has not been fully investigated in the context of severe coronavirus disease (COVID-19) patients. AIM: To investigate environmental SARS-CoV-2 contamination in the isolation rooms of severe COVID-19 patients requiring mechanical ventilation or high-flow oxygen therapy. METHODS: Environmental swab samples and air samples were collected from the isolation rooms of three COVID-19 patients with severe pneumonia. Patients 1 and 2 received mechanical ventilation with a closed suction system, while patient 3 received high-flow oxygen therapy and non-invasive ventilation. Real-time reverse transcription-polymerase chain reaction (rRT-PCR) was used to detect SARS-CoV-2; viral cultures were performed for samples not negative on rRT-PCR. FINDINGS: Of the 48 swab samples collected in the rooms of patients 1 and 2, only samples from the outside surfaces of the endotracheal tubes tested positive for SARS-CoV-2 by rRT-PCR. However, in patient 3's room, 13 of the 28 environmental samples (fomites, fixed structures, and ventilation exit on the ceiling) showed positive results. Air samples were negative for SARS-CoV-2. Viable viruses were identified on the surface of the endotracheal tube of patient 1 and seven sites in patient 3's room. CONCLUSION: Environmental contamination of SARS-CoV-2 may be a route of viral transmission. However, it might be minimized when patients receive mechanical ventilation with a closed suction system. These findings can provide evidence for guidelines for the safe use of personal protective equipment.
  • |*Practice Guidelines as Topic[MESH]
  • |Air Microbiology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*therapy[MESH]
  • |Decontamination/*standards[MESH]
  • |Environmental Pollution/*analysis[MESH]
  • |Humans[MESH]
  • |Hyperbaric Oxygenation/*standards[MESH]
  • |Pandemics[MESH]
  • |Patients' Rooms/*standards[MESH]
  • |Pneumonia, Viral/*therapy[MESH]
  • |Pneumonia/*therapy[MESH]


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