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10.1016/S0140-6736(20)31561-0

http://scihub22266oqcxt.onion/10.1016/S0140-6736(20)31561-0
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32828189!7440877!32828189
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suck abstract from ncbi


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pmid32828189      Lancet 2020 ; 396 (10250): 565-582
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  • Sex and gender: modifiers of health, disease, and medicine #MMPMID32828189
  • Mauvais-Jarvis F; Bairey Merz N; Barnes PJ; Brinton RD; Carrero JJ; DeMeo DL; De Vries GJ; Epperson CN; Govindan R; Klein SL; Lonardo A; Maki PM; McCullough LD; Regitz-Zagrosek V; Regensteiner JG; Rubin JB; Sandberg K; Suzuki A
  • Lancet 2020[Aug]; 396 (10250): 565-582 PMID32828189show ga
  • Clinicians can encounter sex and gender disparities in diagnostic and therapeutic responses. These disparities are noted in epidemiology, pathophysiology, clinical manifestations, disease progression, and response to treatment. This Review discusses the fundamental influences of sex and gender as modifiers of the major causes of death and morbidity. We articulate how the genetic, epigenetic, and hormonal influences of biological sex influence physiology and disease, and how the social constructs of gender affect the behaviour of the community, clinicians, and patients in the health-care system and interact with pathobiology. We aim to guide clinicians and researchers to consider sex and gender in their approach to diagnosis, prevention, and treatment of diseases as a necessary and fundamental step towards precision medicine, which will benefit men's and women's health.
  • |*Cause of Death[MESH]
  • |*Health Status[MESH]
  • |*Sex Distribution[MESH]
  • |Acute Disease/epidemiology[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Chronic Disease/epidemiology[MESH]
  • |Coronavirus Infections/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/epidemiology[MESH]
  • |Precision Medicine/*standards[MESH]
  • |SARS-CoV-2[MESH]
  • |Sex Characteristics[MESH]


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