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10.4049/jimmunol.2000710 http://scihub22266oqcxt.onion/10.4049/jimmunol.2000710 32826281!ä!32826281 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol 2020 ; 205 (8): 1990-1997 Nephropedia Template TP {{tp|p=32826281|t=2020. Neonatal and Children s Immune System and COVID-19: Biased Immune Tolerance versus Resistance Strategy |pdf=|usr=}}{{32826281}} gab.com Text Neonatal and Children s Immune System and COVID-19: Biased Immune Tolerance versus Resistance Strategy JO: J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32826281 #FOAvip The recent outbreak of COVID-19 has emerged as a major global health concern. Although susceptible to infection, recent evidence indicates mostly asymptomatic or mild presentation of the disease in infants, children, and adolescents. Similar observations were made for acute respiratory infections caused by other coronaviruses (severe acute respiratory syndrome and Middle East respiratory syndrome). These observations suggest that the immune system behaves differently in children than adults. Recent developments in the field demonstrated fundamental differences in the neonatal immune system as compared with adults, whereby infants respond to microorganisms through biased immune tolerance rather than resistance strategies. Similarly, more frequent/recent vaccinations in children and younger populations may result in trained immunity. Therefore, the physiological abundance of certain immunosuppressive cells, a tightly regulated immune system, and/or exposure to attenuated vaccines may enhance trained immunity to limit excessive immune reaction to COVID-19 in the young. Twit Text FOAVip Neonatal and Children s Immune System and COVID-19: Biased Immune Tolerance versus Resistance Strategy ????J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32826281 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32826281 #FOAvip English Wikipedia <ref>{{Cite pmid|32826281}}</ref> Neonatal and Children s Immune System and COVID-19: Biased Immune Tolerance versus Resistance Strategy #MMPMID32826281 Elahi S J Immunol 2020[Oct]; 205 (8): 1990-1997 PMID32826281show ga The recent outbreak of COVID-19 has emerged as a major global health concern. Although susceptible to infection, recent evidence indicates mostly asymptomatic or mild presentation of the disease in infants, children, and adolescents. Similar observations were made for acute respiratory infections caused by other coronaviruses (severe acute respiratory syndrome and Middle East respiratory syndrome). These observations suggest that the immune system behaves differently in children than adults. Recent developments in the field demonstrated fundamental differences in the neonatal immune system as compared with adults, whereby infants respond to microorganisms through biased immune tolerance rather than resistance strategies. Similarly, more frequent/recent vaccinations in children and younger populations may result in trained immunity. Therefore, the physiological abundance of certain immunosuppressive cells, a tightly regulated immune system, and/or exposure to attenuated vaccines may enhance trained immunity to limit excessive immune reaction to COVID-19 in the young. |*Immune Tolerance[MESH] |Adolescent[MESH] |Adult[MESH] |Betacoronavirus/*immunology[MESH] |COVID-19[MESH] |Child[MESH] |Child, Preschool[MESH] |Coronavirus Infections/drug therapy/*immunology/virology[MESH] |Disease Susceptibility[MESH] |Humans[MESH] |Immune System/*immunology[MESH] |Immunosuppressive Agents/therapeutic use[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Pandemics[MESH] |Pneumonia, Viral/drug therapy/*immunology/virology[MESH] |SARS-CoV-2[MESH] |Vaccines, Attenuated/immunology[MESH]Neonatal and Children s Immune System and COVID-19: Biased Immune Tole(epmc).pdf DeepDyve Pubget Overpricing