Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/s41385-020-00340-z http://scihub22266oqcxt.onion/10.1038/s41385-020-00340-z 32820248!7439637!32820248     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32820248&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mucosal+Immunol 2020 ; 13 (6): 877-891 Nephropedia Template TP {{tp|p=32820248|t=2020. Animal and translational models of SARS-CoV-2 infection and COVID-19 |pdf=|usr=}}{{32820248}} gab.com Text Animal and translational models of SARS-CoV-2 infection and COVID-19 JO: Mucosal Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32820248 #FOAvip COVID-19 is causing a major once-in-a-century global pandemic. The scientific and clinical community is in a race to define and develop effective preventions and treatments. The major features of disease are described but clinical trials have been hampered by competing interests, small scale, lack of defined patient cohorts and defined readouts. What is needed now is head-to-head comparison of existing drugs, testing of safety including in the background of predisposing chronic diseases, and the development of new and targeted preventions and treatments. This is most efficiently achieved using representative animal models of primary infection including in the background of chronic disease with validation of findings in primary human cells and tissues. We explore and discuss the diverse animal, cell and tissue models that are being used and developed and collectively recapitulate many critical aspects of disease manifestation in humans to develop and test new preventions and treatments. Twit Text FOAVip Animal and translational models of SARS-CoV-2 infection and COVID-19 ????Mucosal Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32820248 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32820248 #FOAvip English Wikipedia <ref>{{Cite pmid|32820248}}</ref> Animal and translational models of SARS-CoV-2 infection and COVID-19 #MMPMID32820248 Johansen MD; Irving A; Montagutelli X; Tate MD; Rudloff I; Nold MF; Hansbro NG; Kim RY; Donovan C; Liu G; Faiz A; Short KR; Lyons JG; McCaughan GW; Gorrell MD; Cole A; Moreno C; Couteur D; Hesselson D; Triccas J; Neely GG; Gamble JR; Simpson SJ; Saunders BM; Oliver BG; Britton WJ; Wark PA; Nold-Petry CA; Hansbro PM Mucosal Immunol 2020[Nov]; 13 (6): 877-891 PMID32820248show ga COVID-19 is causing a major once-in-a-century global pandemic. The scientific and clinical community is in a race to define and develop effective preventions and treatments. The major features of disease are described but clinical trials have been hampered by competing interests, small scale, lack of defined patient cohorts and defined readouts. What is needed now is head-to-head comparison of existing drugs, testing of safety including in the background of predisposing chronic diseases, and the development of new and targeted preventions and treatments. This is most efficiently achieved using representative animal models of primary infection including in the background of chronic disease with validation of findings in primary human cells and tissues. We explore and discuss the diverse animal, cell and tissue models that are being used and developed and collectively recapitulate many critical aspects of disease manifestation in humans to develop and test new preventions and treatments. |*Disease Models, Animal[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Animals[MESH] |Animals, Genetically Modified[MESH] |Antibodies, Viral/*biosynthesis[MESH] |Antiviral Agents/chemical synthesis/*pharmacology[MESH] |Betacoronavirus/drug effects/genetics/*pathogenicity/physiology[MESH] |COVID-19[MESH] |COVID-19 Vaccines[MESH] |Cats[MESH] |Chiroptera[MESH] |Coronavirus Infections/drug therapy/genetics/*immunology/prevention & control/virology[MESH] |Cricetulus[MESH] |Female[MESH] |Ferrets[MESH] |Haplorhini[MESH] |Humans[MESH] |Male[MESH] |Mice[MESH] |Organoids/drug effects/immunology/virology[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/genetics/immunology[MESH] |Pneumonia, Viral/drug therapy/genetics/*immunology/virology[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |Species Specificity[MESH] |Spike Glycoprotein, Coronavirus/genetics/immunology[MESH]Animal and translational models of SARS-CoV-2 infection and COVID-19 (epmc).pdf DeepDyve Pubget Overpricing