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10.1007/s00330-020-07154-4

http://scihub22266oqcxt.onion/10.1007/s00330-020-07154-4
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32813105!7435221!32813105
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suck abstract from ncbi


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pmid32813105      Eur+Radiol 2021 ; 31 (2): 795-803
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  • Chest CT for rapid triage of patients in multiple emergency departments during COVID-19 epidemic: experience report from a large French university hospital #MMPMID32813105
  • Ducray V; Vlachomitrou AS; Bouscambert-Duchamp M; Si-Mohamed S; Gouttard S; Mansuy A; Wickert F; Sigal A; Gaymard A; Talbot F; Michel C; Perpoint T; Pialat JB; Rouviere O; Milot L; Cotton F; Douek P; Rabilloud M; Boussel L
  • Eur Radiol 2021[Feb]; 31 (2): 795-803 PMID32813105show ga
  • OBJECTIVES: To assess the diagnostic performances of chest CT for triage of patients in multiple emergency departments during COVID-19 epidemic, in comparison with reverse transcription polymerase chain reaction (RT-PCR) test. METHOD: From March 3 to April 4, 2020, 694 consecutive patients from three emergency departments of a large university hospital, for which a hospitalization was planned whatever the reasons, i.e., COVID- or non-COVID-related, underwent a chest CT and one or several RT-PCR tests. Chest CTs were rated as "Surely COVID+," "Possible COVID+," or "COVID-" by experienced radiologists. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated using the final RT-PCR test as standard of reference. The delays for CT reports and RT-PCR results were recorded and compared. RESULTS: Among the 694 patients, 287 were positive on the final RT-PCR exam. Concerning the 694 chest CT, 308 were rated as "Surely COVID+", 34 as "Possible COVID+," and 352 as "COVID-." When considering only the "Surely COVID+" CT as positive, accuracy, sensitivity, specificity, PPV, and NPV reached 88.9%, 90.2%, 88%, 84.1%, and 92.7%, respectively, with respect to final RT-PCR test. The mean delay for CT reports was three times shorter than for RT-PCR results (187 +/- 148 min versus 573 +/- 327 min, p < 0.0001). CONCLUSION: During COVID-19 epidemic phase, chest CT is a rapid and most probably an adequately reliable tool to refer patients requiring hospitalization to the COVID+ or COVID- hospital units, when response times for virological tests are too long. KEY POINTS: * In a large university hospital in Lyon, France, the accuracy, sensitivity, specificity, PPV, and NPV of chest CT for COVID-19 reached 88.9%, 90.2%, 88%, 84.1%, and 92.7%, respectively, using RT-PCR as standard of reference. * The mean delay for CT reports was three times shorter than for RT-PCR results (187 +/- 148 min versus 573 +/- 327 min, p < 0.0001). * Due to high accuracy of chest CT for COVID-19 and shorter time for CT reports than RT-PCR results, chest CT can be used to orient patients suspected to be positive towards the COVID+ unit to decrease congestion in the emergency departments.
  • |*Triage[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnostic imaging/epidemiology[MESH]
  • |Emergency Service, Hospital[MESH]
  • |Epidemics[MESH]
  • |Female[MESH]
  • |France[MESH]
  • |Hospitals, University[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Predictive Value of Tests[MESH]
  • |SARS-CoV-2[MESH]
  • |Time Factors[MESH]


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