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10.1093/infdis/jiaa528

http://scihub22266oqcxt.onion/10.1093/infdis/jiaa528
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32812049!7454721!32812049
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suck abstract from ncbi


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pmid32812049      J+Infect+Dis 2020 ; 222 (11): 1789-1793
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  • Circulating Endothelial Cells as a Marker of Endothelial Injury in Severe COVID -19 #MMPMID32812049
  • Guervilly C; Burtey S; Sabatier F; Cauchois R; Lano G; Abdili E; Daviet F; Arnaud L; Brunet P; Hraiech S; Jourde-Chiche N; Koubi M; Lacroix R; Pietri L; Berda Y; Robert T; Degioanni C; Velier M; Papazian L; Kaplanski G; Dignat-George F
  • J Infect Dis 2020[Nov]; 222 (11): 1789-1793 PMID32812049show ga
  • Beside the commonly described pulmonary expression of the coronavirus disease 2019 (COVID-19), major vascular events have been reported. The objective of this study was to investigate whether increased levels of circulating endothelial cells (CECs) might be associated with severe forms of COVID-19. Ninety-nine patients with COVID-19 were enrolled in this retrospective study. Patients in the intensive care units (ICU) had significantly higher CEC counts than non-ICU patients and the extent of endothelial injury was correlated with putative markers of disease severity and inflammatory cytokines. Together, these data provide in vivo evidence that endothelial injury is a key feature of COVID-19.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Biomarkers/analysis[MESH]
  • |COVID-19/blood/*pathology/virology[MESH]
  • |Cell Adhesion/physiology[MESH]
  • |Endothelium, Vascular/*pathology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]


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