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10.1016/j.ejrad.2020.109209

http://scihub22266oqcxt.onion/10.1016/j.ejrad.2020.109209
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suck abstract from ncbi


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pmid32810701      Eur+J+Radiol 2020 ; 131 (ä): 109209
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  • COVID-19 pneumonia: Diagnostic and prognostic role of CT based on a retrospective analysis of 214 consecutive patients from Paris, France #MMPMID32810701
  • Guillo E; Bedmar Gomez I; Dangeard S; Bennani S; Saab I; Tordjman M; Jilet L; Chassagnon G; Revel MP
  • Eur J Radiol 2020[Oct]; 131 (ä): 109209 PMID32810701show ga
  • OBJECTIVES: To evaluate the diagnostic and prognostic performance of CT in patients referred for COVID19 suspicion to a French university hospital, depending on symptoms and date of onset. METHODS: From March 1st to March 28th, 214 patients having both chest CT scan and reverse transcriptase polymerase chain reaction (RT- PCT) within 24?h were retrospectively evaluated. Sensitivity, specificity, negative and positive predictive values of first and expert readings were calculated together with inter reader agreement, with results of RT-PCR as standard of reference and according to symptoms and onset date. Patient characteristics and disease extent on CT were correlated to short-term outcome (death or intubation at 3 weeks follow-up). RESULTS: Of the 214 patients (119 men, mean age 59?+/-?19 years), 129 had at least one positive RT-PCR result. Sensitivity, specificity, negative and positive predictive values were 79 % (95 % CI: 71-86 %), 84 %(74-91 %), 72 %(63-81 %) and 88 % (81-93 %) for initial CT reading and 81 %(74-88 %), 91 % (82-96 %), 76 % (67-84 %) and 93 % (87-97 %), for expert reading, with strong inter-reader agreement (kappa index: 0.89). Considering the 123 patients with symptoms for more than 5 days, the corresponding figures were 90 %, 78 %, 80 % and 89 % for initial reading and 93 %, 88 %, 86 % and 94 % for the expert. Disease extent exceeded 25 % for 68 % and 26 % of severe and non-severe patients, respectively (p? 25 % was associated with poorer outcome.
  • |*Betacoronavirus[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*diagnostic imaging[MESH]
  • |Female[MESH]
  • |France[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnostic imaging[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Thorax[MESH]


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