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  • Updates on community acquired pneumonia management in the ICU #MMPMID32805298
  • Nair GB; Niederman MS
  • Pharmacol Ther 2021[Jan]; 217 (ä): 107663 PMID32805298show ga
  • While the world is grappling with the consequences of a global pandemic related to SARS-CoV-2 causing severe pneumonia, available evidence points to bacterial infection with Streptococcus pneumoniae as the most common cause of severe community acquired pneumonia (SCAP). Rapid diagnostics and molecular testing have improved the identification of co-existent pathogens. However, mortality in patients admitted to ICU remains staggeringly high. The American Thoracic Society and Infectious Diseases Society of America have updated CAP guidelines to help streamline disease management. The common theme is use of timely, appropriate and adequate antibiotic coverage to decrease mortality and avoid drug resistance. Novel antibiotics have been studied for CAP and extend the choice of therapy, particularly for those who are intolerant of, or not responding to standard treatment, including those who harbor drug resistant pathogens. In this review, we focus on the risk factors, microbiology, site of care decisions and treatment of patients with SCAP.
  • |*Disease Management[MESH]
  • |*Intensive Care Units[MESH]
  • |Community-Acquired Infections/*drug therapy/*microbiology/mortality[MESH]
  • |Drug Resistance, Multiple, Bacterial[MESH]
  • |Guidelines as Topic[MESH]
  • |Humans[MESH]
  • |Pneumonia/*drug therapy/*microbiology/mortality[MESH]

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  • suck abstract from ncbi

    107663 ä.217 2021