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10.1111/sji.12960 http://scihub22266oqcxt.onion/10.1111/sji.12960 32797724!7461012!32797724     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Scand+J+Immunol 2021 ; 93 (2): e12960 Nephropedia Template TP {{tp|p=32797724|t=2021. The potential involvement of P2X7 receptor in COVID-19 pathogenesis: A new therapeutic target?|pdf=|usr=}}{{32797724}} gab.com Text The potential involvement of P2X7 receptor in COVID-19 pathogenesis: A new therapeutic target JO: Scand J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32797724 #FOAvip Coronavirus disease 2019 (COVID-19) pathogenesis remains under investigation. Growing evidence indicates the establishment of a hyperinflammatory response, characterized by sustained production of cytokines, such as IL-1beta. The release and maturation of this cytokine are dependent on the activation of a catalytic multiprotein complex, known as "inflammasome". The most investigated is the NLRP3 inflammasome, which can be activated by various stimuli, such as the recognition of extracellular ATP by the P2X7 receptor. Based on the recent literature, we present evidence that supports the idea that the P2X7R/NLRP3 axis may be involved in the immune dysregulation caused by the SARS-CoV-2 infection. Twit Text FOAVip The potential involvement of P2X7 receptor in COVID-19 pathogenesis: A new therapeutic target ????Scand J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32797724 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32797724 #FOAvip English Wikipedia <ref>{{Cite pmid|32797724}}</ref> The potential involvement of P2X7 receptor in COVID-19 pathogenesis: A new therapeutic target? #MMPMID32797724 Pacheco PAF; Faria RX Scand J Immunol 2021[Feb]; 93 (2): e12960 PMID32797724show ga Coronavirus disease 2019 (COVID-19) pathogenesis remains under investigation. Growing evidence indicates the establishment of a hyperinflammatory response, characterized by sustained production of cytokines, such as IL-1beta. The release and maturation of this cytokine are dependent on the activation of a catalytic multiprotein complex, known as "inflammasome". The most investigated is the NLRP3 inflammasome, which can be activated by various stimuli, such as the recognition of extracellular ATP by the P2X7 receptor. Based on the recent literature, we present evidence that supports the idea that the P2X7R/NLRP3 axis may be involved in the immune dysregulation caused by the SARS-CoV-2 infection. |Animals[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/*immunology[MESH] |Humans[MESH] |Inflammasomes/physiology[MESH] |NLR Family, Pyrin Domain-Containing 3 Protein/physiology[MESH] |Receptors, Purinergic P2X7/drug effects/*physiology[MESH]The potential involvement of P2X7 receptor in COVID-19 pathogenesis: A(epmc).pdf DeepDyve Pubget Overpricing