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10.1038/s41467-020-17971-2

http://scihub22266oqcxt.onion/10.1038/s41467-020-17971-2
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suck abstract from ncbi


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pmid32796848      Nat+Commun 2020 ; 11 (1): 4080
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  • Artificial intelligence for the detection of COVID-19 pneumonia on chest CT using multinational datasets #MMPMID32796848
  • Harmon SA; Sanford TH; Xu S; Turkbey EB; Roth H; Xu Z; Yang D; Myronenko A; Anderson V; Amalou A; Blain M; Kassin M; Long D; Varble N; Walker SM; Bagci U; Ierardi AM; Stellato E; Plensich GG; Franceschelli G; Girlando C; Irmici G; Labella D; Hammoud D; Malayeri A; Jones E; Summers RM; Choyke PL; Xu D; Flores M; Tamura K; Obinata H; Mori H; Patella F; Cariati M; Carrafiello G; An P; Wood BJ; Turkbey B
  • Nat Commun 2020[Aug]; 11 (1): 4080 PMID32796848show ga
  • Chest CT is emerging as a valuable diagnostic tool for clinical management of COVID-19 associated lung disease. Artificial intelligence (AI) has the potential to aid in rapid evaluation of CT scans for differentiation of COVID-19 findings from other clinical entities. Here we show that a series of deep learning algorithms, trained in a diverse multinational cohort of 1280 patients to localize parietal pleura/lung parenchyma followed by classification of COVID-19 pneumonia, can achieve up to 90.8% accuracy, with 84% sensitivity and 93% specificity, as evaluated in an independent test set (not included in training and validation) of 1337 patients. Normal controls included chest CTs from oncology, emergency, and pneumonia-related indications. The false positive rate in 140 patients with laboratory confirmed other (non COVID-19) pneumonias was 10%. AI-based algorithms can readily identify CT scans with COVID-19 associated pneumonia, as well as distinguish non-COVID related pneumonias with high specificity in diverse patient populations.
  • |*Artificial Intelligence[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Algorithms[MESH]
  • |Betacoronavirus/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Clinical Laboratory Techniques/*methods[MESH]
  • |Coronavirus Infections/diagnosis/*diagnostic imaging/virology[MESH]
  • |Deep Learning[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Imaging, Three-Dimensional/methods[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnostic imaging/virology[MESH]
  • |Radiographic Image Interpretation, Computer-Assisted/methods[MESH]
  • |SARS-CoV-2[MESH]
  • |Tomography, X-Ray Computed/*methods[MESH]


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