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10.1007/s10140-020-01838-6

http://scihub22266oqcxt.onion/10.1007/s10140-020-01838-6
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32789807!7424559!32789807
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suck abstract from ncbi


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pmid32789807      Emerg+Radiol 2020 ; 27 (6): 607-615
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  • A low-dose chest CT protocol for the diagnosis of COVID-19 pneumonia: a prospective study #MMPMID32789807
  • Tabatabaei SMH; Talari H; Gholamrezanezhad A; Farhood B; Rahimi H; Razzaghi R; Mehri N; Rajebi H
  • Emerg Radiol 2020[Dec]; 27 (6): 607-615 PMID32789807show ga
  • PURPOSE: The increasing trend of chest CT utilization during the COVID-19 pandemic necessitates novel protocols with reduced dose and maintained diagnostic accuracy. We aimed to investigate the diagnostic accuracy of 30-mAs chest CT protocol in comparison with a 150-mAs standard-dose routine protocol for imaging of COVID-19 pneumonia. METHODS: Upon IRB approval, consecutive laboratory-confirmed positive COVID-19 patients aged 50 years or older who were referred for chest CT scan and had same-day normal CXR were invited to participate in this prospective study. First, a standard-dose chest CT scan (150 mAs) was performed. Only if typical COVID-19 pneumonia features were identified, then a low-dose CT (30 mAs) was done immediately. Diagnostic accuracy of low-dose and standard-dose CT in the detection of typical COVID-19 pneumonia features were compared. RESULTS: Twenty patients with a mean age of 64.20 +/- 13.8 were enrolled in the study. There was excellent intrareader agreement in detecting typical findings of COVID-19 pneumonia between low-dose and standard-dose (intraclass correlation coefficient [ICC] = 0.98-0.99, P values < 0.001 all readers). The mean effective dose values in standard- and low-dose groups were 6.60 +/- 1.47 and 1.80 +/- 0.42 mSv, respectively. Also, absolute cancer risk per mean cumulative effective dose values obtained from the standard- and low-dose CT examinations were 2.71 x 10(-4) and 0.74 x 10(-4), respectively. CONCLUSIONS: According to our study, it was found that proposed low-dose CT chest protocol is reliable in detecting COVID-19 pneumonia in daily practice with significant reduction in radiation dose and estimated cancer risk.
  • |Aged[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*diagnostic imaging[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnostic imaging[MESH]
  • |Prospective Studies[MESH]
  • |Radiation Dosage[MESH]
  • |Radiography, Thoracic/*methods[MESH]
  • |SARS-CoV-2[MESH]


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