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10.1074/mcp.RP120.002128 http://scihub22266oqcxt.onion/10.1074/mcp.RP120.002128 32788344!7664125!32788344     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Cell+Proteomics 2020 ; 19 (11): 1749-1759 Nephropedia Template TP {{tp|p=32788344|t=2020. Serum Protein Profiling Reveals a Landscape of Inflammation and Immune Signaling in Early-stage COVID-19 Infection |pdf=|usr=}}{{32788344}} gab.com Text Serum Protein Profiling Reveals a Landscape of Inflammation and Immune Signaling in Early-stage COVID-19 Infection JO: Mol Cell Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=32788344 #FOAvip Coronavirus disease 2019 (COVID-19) is a highly contagious infection and threating the human lives in the world. The elevation of cytokines in blood is crucial to induce cytokine storm and immunosuppression in the transition of severity in COVID-19 patients. However, the comprehensive changes of serum proteins in COVID-19 patients throughout the SARS-CoV-2 infection is unknown. In this work, we developed a high-density antibody microarray and performed an in-depth proteomics analysis of serum samples collected from early COVID-19 (n = 15) and influenza (n = 13) patients. We identified a large set of differentially expressed proteins (n = 132) that participate in a landscape of inflammation and immune signaling related to the SARS-CoV-2 infection. Furthermore, the significant correlations of neutrophil and lymphocyte with the CCL2 and CXCL10 mediated cytokine signaling pathways was identified. These information are valuable for the understanding of COVID-19 pathogenesis, identification of biomarkers and development of the optimal anti-inflammation therapy. Twit Text FOAVip Serum Protein Profiling Reveals a Landscape of Inflammation and Immune Signaling in Early-stage COVID-19 Infection ????Mol Cell Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=32788344 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32788344 #FOAvip English Wikipedia <ref>{{Cite pmid|32788344}}</ref> Serum Protein Profiling Reveals a Landscape of Inflammation and Immune Signaling in Early-stage COVID-19 Infection #MMPMID32788344 Hou X; Zhang X; Wu X; Lu M; Wang D; Xu M; Wang H; Liang T; Dai J; Duan H; Xu Y; Yu X; Li Y Mol Cell Proteomics 2020[Nov]; 19 (11): 1749-1759 PMID32788344show ga Coronavirus disease 2019 (COVID-19) is a highly contagious infection and threating the human lives in the world. The elevation of cytokines in blood is crucial to induce cytokine storm and immunosuppression in the transition of severity in COVID-19 patients. However, the comprehensive changes of serum proteins in COVID-19 patients throughout the SARS-CoV-2 infection is unknown. In this work, we developed a high-density antibody microarray and performed an in-depth proteomics analysis of serum samples collected from early COVID-19 (n = 15) and influenza (n = 13) patients. We identified a large set of differentially expressed proteins (n = 132) that participate in a landscape of inflammation and immune signaling related to the SARS-CoV-2 infection. Furthermore, the significant correlations of neutrophil and lymphocyte with the CCL2 and CXCL10 mediated cytokine signaling pathways was identified. These information are valuable for the understanding of COVID-19 pathogenesis, identification of biomarkers and development of the optimal anti-inflammation therapy. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Betacoronavirus/pathogenicity[MESH] |Blood Proteins/genetics/*immunology[MESH] |COVID-19[MESH] |Child[MESH] |Coronavirus Infections/genetics/*immunology/physiopathology/virology[MESH] |Cough/genetics/*immunology/physiopathology/virology[MESH] |Cytokine Release Syndrome/genetics/*immunology/physiopathology/virology[MESH] |Cytokines/genetics/immunology[MESH] |Female[MESH] |Fever/genetics/*immunology/physiopathology/virology[MESH] |Gene Expression Profiling[MESH] |Gene Expression Regulation[MESH] |Headache/genetics/*immunology/physiopathology/virology[MESH] |Humans[MESH] |Influenza, Human/genetics/*immunology/physiopathology/virology[MESH] |Male[MESH] |Middle Aged[MESH] |Myalgia/genetics/*immunology/physiopathology/virology[MESH] |Orthomyxoviridae/pathogenicity[MESH] |Pandemics[MESH] |Pneumonia, Viral/genetics/*immunology/physiopathology/virology[MESH] |Protein Array Analysis[MESH] |Proteome/genetics/immunology[MESH] |Receptors, Cytokine/genetics/immunology[MESH] |SARS-CoV-2[MESH]Serum Protein Profiling Reveals a Landscape of Inflammation and Immune(epmc).pdf DeepDyve Pubget Overpricing