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10.1177/2324709620950107

http://scihub22266oqcxt.onion/10.1177/2324709620950107
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32787459!7427003!32787459
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suck abstract from ncbi


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pmid32787459      J+Investig+Med+High+Impact+Case+Rep 2020 ; 8 (ä): 2324709620950107
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  • Epstein-Barr Virus Versus Novel Coronavirus-Induced Hemophagocytic Lymphohistocytosis: The Uncharted Waters #MMPMID32787459
  • Amir R; Kichloo A; Singh J; Bhanot R; Aljadah M; Kumar A; Albosta MS; Solanki S
  • J Investig Med High Impact Case Rep 2020[Jan]; 8 (ä): 2324709620950107 PMID32787459show ga
  • Hemophagocytic lymphohistocytosis (HLH) is a hyperinflammatory syndrome characterized by fever, hepatosplenomegaly, and pancytopenia. It may be associated with genetic mutations or viral/bacterial infections, most commonly Epstein-Barr virus (EBV) and cytomegalovirus. As for the novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), also known as COVID-19 (coronavirus disease-2019), the cytokine storm it triggers can theoretically lead to syndromes similar to HLH. In this article, we report a case of a 28-year-old female who presented with high-grade fevers, found to have both SARS-CoV-2 and EBV infections, and eventually began to show signs of early HLH. To our knowledge, this is the first case reported in literature that raises the possibility of SARS-CoV-2-related HLH development.
  • |Adult[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications/diagnosis[MESH]
  • |Epstein-Barr Virus Infections/complications/*diagnosis[MESH]
  • |Female[MESH]
  • |Herpesvirus 4, Human/*isolation & purification[MESH]
  • |Humans[MESH]
  • |Lymphohistiocytosis, Hemophagocytic/*immunology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/diagnosis[MESH]


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