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10.3390/genes11080918 http://scihub22266oqcxt.onion/10.3390/genes11080918 32785186!7464837!32785186     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+(Basel) 2020 ; 11 (8): ä Nephropedia Template TP {{tp|p=32785186|t=2020. The Characterization of chIFITMs in Avian Coronavirus Infection In Vivo, Ex Vivo and In Vitro |pdf=|usr=}}{{32785186}} gab.com Text The Characterization of chIFITMs in Avian Coronavirus Infection In Vivo, Ex Vivo and In Vitro JO: Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=32785186 #FOAvip The coronaviruses are a large family of enveloped RNA viruses that commonly cause gastrointestinal or respiratory illnesses in the infected host. Avian coronavirus infectious bronchitis virus (IBV) is a highly contagious respiratory pathogen of chickens that can affect the kidneys and reproductive systems resulting in bird mortality and decreased reproductivity. The interferon-inducible transmembrane (IFITM) proteins are activated in response to viral infections and represent a class of cellular restriction factors that restrict the replication of many viral pathogens. Here, we characterize the relative mRNA expression of the chicken IFITM genes in response to IBV infection, in vivo, ex vivo and in vitro using the pathogenic M41-CK strain, the nephropathogenic QX strain and the nonpathogenic Beaudette strain. In vivo we demonstrate a significant upregulation of chIFITM1, 2, 3 and 5 in M41-CK- and QX-infected trachea two days post-infection. In vitro infection with Beaudette, M41-CK and QX results in a significant upregulation of chIFITM1, 2 and 3 at 24 h post-infection. We confirmed a differential innate response following infection with distinct IBV strains and believe that our data provide new insights into the possible role of chIFITMs in early IBV infection. Twit Text FOAVip The Characterization of chIFITMs in Avian Coronavirus Infection In Vivo, Ex Vivo and In Vitro ????Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=32785186 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32785186 #FOAvip English Wikipedia <ref>{{Cite pmid|32785186}}</ref> The Characterization of chIFITMs in Avian Coronavirus Infection In Vivo, Ex Vivo and In Vitro #MMPMID32785186 Steyn A; Keep S; Bickerton E; Fife M Genes (Basel) 2020[Aug]; 11 (8): ä PMID32785186show ga The coronaviruses are a large family of enveloped RNA viruses that commonly cause gastrointestinal or respiratory illnesses in the infected host. Avian coronavirus infectious bronchitis virus (IBV) is a highly contagious respiratory pathogen of chickens that can affect the kidneys and reproductive systems resulting in bird mortality and decreased reproductivity. The interferon-inducible transmembrane (IFITM) proteins are activated in response to viral infections and represent a class of cellular restriction factors that restrict the replication of many viral pathogens. Here, we characterize the relative mRNA expression of the chicken IFITM genes in response to IBV infection, in vivo, ex vivo and in vitro using the pathogenic M41-CK strain, the nephropathogenic QX strain and the nonpathogenic Beaudette strain. In vivo we demonstrate a significant upregulation of chIFITM1, 2, 3 and 5 in M41-CK- and QX-infected trachea two days post-infection. In vitro infection with Beaudette, M41-CK and QX results in a significant upregulation of chIFITM1, 2 and 3 at 24 h post-infection. We confirmed a differential innate response following infection with distinct IBV strains and believe that our data provide new insights into the possible role of chIFITMs in early IBV infection. |Animals[MESH] |Chickens/*genetics/*virology[MESH] |Coronavirus Infections/genetics/*veterinary[MESH] |Gene Expression Regulation, Viral[MESH] |Host-Pathogen Interactions/*genetics/physiology[MESH] |Infectious bronchitis virus/pathogenicity/physiology[MESH] |Membrane Proteins/*genetics[MESH] |Organ Culture Techniques[MESH] |Poultry Diseases/etiology/genetics/virology[MESH] |Viral Load[MESH]The Characterization of chIFITMs in Avian Coronavirus Infection In Viv(epmc).pdf DeepDyve Pubget Overpricing