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10.1016/j.jped.2020.07.002 http://scihub22266oqcxt.onion/10.1016/j.jped.2020.07.002 32781034!7402103!32781034     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Pediatr+(Rio+J) 2020 ; 96 (5): 582-592 Nephropedia Template TP {{tp|p=32781034|t=2020. Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study |pdf=|usr=}}{{32781034}} gab.com Text Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study JO: J Pediatr (Rio J) http://www.kidney.de/pget.php?&tw=1&pmid=32781034 #FOAvip OBJECTIVE: To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID-19. METHOD: Prospective, multicenter, observational study, in 19 pediatric intensive care units. Patients aged 1 month to 19 years admitted consecutively (March-May 2020) were included. Demographic, clinical-epidemiological features, treatment, and outcomes were collected. Subgroups were compared according to comorbidities, age < 1?year, and need for invasive mechanical ventilation. A multivariable logistic regression model was used for predictors of severity. RESULTS: Seventy-nine patients were included (ten with multisystemic inflammatory syndrome). Median age 4 years; 54% male (multisystemic inflammatory syndrome, 80%); 41% had comorbidities (multisystemic inflammatory syndrome, 20%). Fever (76%), cough (51%), and tachypnea (50%) were common in both groups. Severe symptoms, gastrointestinal symptoms, and higher inflammatory markers were more frequent in multisystemic inflammatory syndrome. Interstitial lung infiltrates were common in both groups, but pleural effusion was more prevalent in the multisystemic inflammatory syndrome group (43% vs. 14%). Invasive mechanical ventilation was used in 18% (median 7.5 days); antibiotics, oseltamivir, and corticosteroids were used in 76%, 43%, and 23%, respectively, but not hydroxychloroquine. The median pediatric intensive care unit length-of-stay was five days; there were two deaths (3%) in the non- multisystemic inflammatory syndrome group. Patients with comorbidities were older and comorbidities were independently associated with the need for invasive mechanical ventilation (OR 5.5; 95% CI, 1.43-21.12; p?=?0.01). CONCLUSIONS: In Brazilian pediatric intensive care units, COVID-19 had low mortality, age less than 1?year was not associated with a worse prognosis, and patients with multisystemic inflammatory syndrome had more severe symptoms, higher inflammatory biomarkers, and a greater predominance of males, but only comorbidities and chronic diseases were independent predictors of severity. Twit Text FOAVip Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study ????J Pediatr (Rio J) http://www.kidney.de/pget.php?&tw=1&pmid=32781034 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32781034 #FOAvip English Wikipedia <ref>{{Cite pmid|32781034}}</ref> Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study #MMPMID32781034 Prata-Barbosa A; Lima-Setta F; Santos GRD; Lanziotti VS; de Castro REV; de Souza DC; Raymundo CE; de Oliveira FRC; de Lima LFP; Tonial CT; Colleti J Jr; Bellinat APN; Lorenzo VB; Zeitel RS; Pulcheri L; Costa FCMD; La Torre FPF; Figueiredo EADN; Silva TPD; Riveiro PM; Mota ICFD; Brandao IB; de Azevedo ZMA; Gregory SC; Boedo FRO; de Carvalho RN; Castro NAASR; Genu DHS; Foronda FAK; Cunha AJLA; de Magalhaes-Barbosa MC J Pediatr (Rio J) 2020[Sep]; 96 (5): 582-592 PMID32781034show ga OBJECTIVE: To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID-19. METHOD: Prospective, multicenter, observational study, in 19 pediatric intensive care units. Patients aged 1 month to 19 years admitted consecutively (March-May 2020) were included. Demographic, clinical-epidemiological features, treatment, and outcomes were collected. Subgroups were compared according to comorbidities, age < 1?year, and need for invasive mechanical ventilation. A multivariable logistic regression model was used for predictors of severity. RESULTS: Seventy-nine patients were included (ten with multisystemic inflammatory syndrome). Median age 4 years; 54% male (multisystemic inflammatory syndrome, 80%); 41% had comorbidities (multisystemic inflammatory syndrome, 20%). Fever (76%), cough (51%), and tachypnea (50%) were common in both groups. Severe symptoms, gastrointestinal symptoms, and higher inflammatory markers were more frequent in multisystemic inflammatory syndrome. Interstitial lung infiltrates were common in both groups, but pleural effusion was more prevalent in the multisystemic inflammatory syndrome group (43% vs. 14%). Invasive mechanical ventilation was used in 18% (median 7.5 days); antibiotics, oseltamivir, and corticosteroids were used in 76%, 43%, and 23%, respectively, but not hydroxychloroquine. The median pediatric intensive care unit length-of-stay was five days; there were two deaths (3%) in the non- multisystemic inflammatory syndrome group. Patients with comorbidities were older and comorbidities were independently associated with the need for invasive mechanical ventilation (OR 5.5; 95% CI, 1.43-21.12; p?=?0.01). CONCLUSIONS: In Brazilian pediatric intensive care units, COVID-19 had low mortality, age less than 1?year was not associated with a worse prognosis, and patients with multisystemic inflammatory syndrome had more severe symptoms, higher inflammatory biomarkers, and a greater predominance of males, but only comorbidities and chronic diseases were independent predictors of severity. |*Pandemics[MESH] |*Systemic Inflammatory Response Syndrome[MESH] |Adolescent[MESH] |Betacoronavirus[MESH] |Brazil[MESH] |COVID-19[MESH] |Child[MESH] |Child, Preschool[MESH] |Coronavirus Infections/epidemiology/*therapy[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Intensive Care Units, Pediatric/*statistics & numerical data[MESH] |Length of Stay/statistics & numerical data[MESH] |Male[MESH] |Pneumonia, Viral/epidemiology/*therapy[MESH] |Prospective Studies[MESH] |Respiration, Artificial/*methods/statistics & numerical data[MESH]Pediatric patients with COVID-19 admitted to intensive care units in B(epmc).pdf DeepDyve Pubget Overpricing