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10.1111/ijlh.13288

http://scihub22266oqcxt.onion/10.1111/ijlh.13288
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32779838!7405282!32779838
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suck abstract from ncbi


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pmid32779838      Int+J+Lab+Hematol 2020 ; 42 (6): 761-765
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  • Absolute lymphocyte count is a prognostic marker in Covid-19: A retrospective cohort review #MMPMID32779838
  • Wagner J; DuPont A; Larson S; Cash B; Farooq A
  • Int J Lab Hematol 2020[Dec]; 42 (6): 761-765 PMID32779838show ga
  • INTRODUCTION: Prognostic factors are needed to aid clinicians in managing Covid-19, a respiratory illness. Lymphocytopenia has emerged as a simply obtained laboratory value that may correlate with prognosis. METHODS: In this article, we perform a retrospective cohort review study on patients admitted to one academic hospital for Covid-19 illness. We analyzed basic demographic, clinical, and laboratory data to understand the relationship between lymphocytopenia at the time of hospital admission and clinical outcomes. RESULTS: We discovered that lymphocyte count is lower (P = .01) and lymphocytopenia more frequent by an odds ratio of 3.40 (95% CI: 1.06-10.96; P = .04) in patients admitted to the Intensive Care Unit (ICU), a marker of disease severity, relative to those who were not. We additionally find that patients with lymphocytopenia were more likely to develop an acute kidney injury (AKI), a marker of organ failure, during admission by an odds ratio of 4.29 (95% CI: 1.35-13.57; P = .01). CONCLUSION: This evidence supports the hypothesis that lymphocytopenia can be an early, useful, and easily obtained, prognostic factor in determining the clinical course and disease severity of a patient admitted to the hospital for Covid-19.
  • |*Lymphocyte Count[MESH]
  • |Acute Kidney Injury/blood/epidemiology/etiology[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Anemia/etiology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*blood/complications/drug therapy/mortality[MESH]
  • |Female[MESH]
  • |Hospitals, Teaching/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Intubation, Intratracheal/statistics & numerical data[MESH]
  • |Lymphopenia/etiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Odds Ratio[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*blood/complications/drug therapy/mortality[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |Texas/epidemiology[MESH]


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