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10.1111/aor.13786 http://scihub22266oqcxt.onion/10.1111/aor.13786 32779737!7404740!32779737     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Artif+Organs 2020 ; 44 (12): 1296-1302 Nephropedia Template TP {{tp|p=32779737|t=2020. The absorbing filter Oxiris in severe coronavirus disease 2019 patients: A case series |pdf=|usr=}}{{32779737}} gab.com Text The absorbing filter Oxiris in severe coronavirus disease 2019 patients: A case series JO: Artif Organs http://www.kidney.de/pget.php?&tw=1&pmid=32779737 #FOAvip Hypercytokines cause acute respiratory distress syndrome (ARDS) in coronavirus disease 2019 (COVID-19) patients, which is the main reason for intensive care unit treatment and the leading cause of death in COVID-19 patients. Cytokine storm is a critical factor in the development of ARDS. This study evaluated the efficacy and safety of Oxiris filter in the treatment of COVID-19 patients. Five patients with COVID-19 who received continuous renal replacement therapy (CRRT) in Henan provincial people's hospital between January 23, 2019 and March 28, 2020, were enrolled in this study. Heart rate (HR), mean arterial pressure (MAP), oxygenation index (PaO(2) /FiO(2) ), renal function, C-reactive protein (CRP), cytokines, procalcitonin (PCT), acute physiology and chronic health evaluation II (APACHE II), sequential organ failure score (SOFA), and prognosis were compared after CRRT. Five COVID-19 patients, three males and two females, aged 70.2 +/- 19.6 years, were enrolled. After treatment, HR (101.4 +/- 14.08 vs. 83.8 +/- 6.22 bpm/min), CRP (183 +/- 25.21 vs. 93.78 +/- 70.81 mg/L), IL-6 (3234.49 (713.51, 16038.36) vs. 181.29 (82.24, 521.39) pg/mL), IL-8 (154.86 (63.97, 1476.1) vs. 67.19 (27.84, 85.57) pg/mL), and IL-10 (17.43 (9.14, 41.22) vs. 4.97 (2.39, 8.70) pg/mL), APACHE II (29 +/- 4.92 vs. 18.4 +/- 2.07), and SOFA (17.2 +/- 1.92 vs. 11.2 +/- 3.4) significantly decreased (P < .05), while MAP (75.8 +/- 4.92 vs. 85.8 +/- 6.18 mm Hg), and PaO(2) /FiO(2) (101.2 +/- 7.49 vs. 132.6 +/- 26.15 mm Hg) significantly increased (P < .05). Among the five patients, negative conversion of nucleic acid test was found in three cases, while two cases died. No adverse events occurred during the treatment. Our study observed a reduced level of overexpressed cytokines, stabilization of hemodynamic status, and staged improvement of organ function during the treatment with Oxiris filter. Twit Text FOAVip The absorbing filter Oxiris in severe coronavirus disease 2019 patients: A case series ????Artif Organs http://www.kidney.de/pget.php?&tw=1&pmid=32779737 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32779737 #FOAvip English Wikipedia <ref>{{Cite pmid|32779737}}</ref> The absorbing filter Oxiris in severe coronavirus disease 2019 patients: A case series #MMPMID32779737 Zhang H; Zhu G; Yan L; Lu Y; Fang Q; Shao F Artif Organs 2020[Dec]; 44 (12): 1296-1302 PMID32779737show ga Hypercytokines cause acute respiratory distress syndrome (ARDS) in coronavirus disease 2019 (COVID-19) patients, which is the main reason for intensive care unit treatment and the leading cause of death in COVID-19 patients. Cytokine storm is a critical factor in the development of ARDS. This study evaluated the efficacy and safety of Oxiris filter in the treatment of COVID-19 patients. Five patients with COVID-19 who received continuous renal replacement therapy (CRRT) in Henan provincial people's hospital between January 23, 2019 and March 28, 2020, were enrolled in this study. Heart rate (HR), mean arterial pressure (MAP), oxygenation index (PaO(2) /FiO(2) ), renal function, C-reactive protein (CRP), cytokines, procalcitonin (PCT), acute physiology and chronic health evaluation II (APACHE II), sequential organ failure score (SOFA), and prognosis were compared after CRRT. Five COVID-19 patients, three males and two females, aged 70.2 +/- 19.6 years, were enrolled. After treatment, HR (101.4 +/- 14.08 vs. 83.8 +/- 6.22 bpm/min), CRP (183 +/- 25.21 vs. 93.78 +/- 70.81 mg/L), IL-6 (3234.49 (713.51, 16038.36) vs. 181.29 (82.24, 521.39) pg/mL), IL-8 (154.86 (63.97, 1476.1) vs. 67.19 (27.84, 85.57) pg/mL), and IL-10 (17.43 (9.14, 41.22) vs. 4.97 (2.39, 8.70) pg/mL), APACHE II (29 +/- 4.92 vs. 18.4 +/- 2.07), and SOFA (17.2 +/- 1.92 vs. 11.2 +/- 3.4) significantly decreased (P < .05), while MAP (75.8 +/- 4.92 vs. 85.8 +/- 6.18 mm Hg), and PaO(2) /FiO(2) (101.2 +/- 7.49 vs. 132.6 +/- 26.15 mm Hg) significantly increased (P < .05). Among the five patients, negative conversion of nucleic acid test was found in three cases, while two cases died. No adverse events occurred during the treatment. Our study observed a reduced level of overexpressed cytokines, stabilization of hemodynamic status, and staged improvement of organ function during the treatment with Oxiris filter. |*Membranes, Artificial[MESH] |APACHE[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Blood Pressure[MESH] |C-Reactive Protein/analysis[MESH] |COVID-19/complications/*therapy[MESH] |Continuous Renal Replacement Therapy/*instrumentation[MESH] |Cytokine Release Syndrome/complications/*prevention & control[MESH] |Female[MESH] |Heart Rate[MESH] |Humans[MESH] |Interleukins/blood[MESH] |Male[MESH] |Middle Aged[MESH] |Organ Dysfunction Scores[MESH] |Oxygen/blood[MESH] |Respiratory Distress Syndrome/*prevention & control/virology[MESH]The absorbing filter Oxiris in severe coronavirus disease 2019 patient(epmc).pdf DeepDyve Pubget Overpricing