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10.1016/j.thromres.2020.07.047 http://scihub22266oqcxt.onion/10.1016/j.thromres.2020.07.047 32777639!7384402!32777639     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Thromb+Res 2020 ; 195 (ä): 219-225 Nephropedia Template TP {{tp|p=32777639|t=2020. D-dimer level is associated with the severity of COVID-19 |pdf=|usr=}}{{32777639}} gab.com Text D-dimer level is associated with the severity of COVID-19 JO: Thromb Res http://www.kidney.de/pget.php?&tw=1&pmid=32777639 #FOAvip INTRODUCTION: Abnormal coagulation function has been demonstrated to be involved in the disease progression of COVID-19. However, the association between D-dimer levels and the severity of COVID-19 is not clear. The study was aimed to investigate the association between D-dimer levels and the severity of COVID-19 based on a cohort study and meta-analysis. MATERIALS AND METHODS: Demographic and clinical data of all confirmed cases with COVID-19 on admission to Tongji Hospital from January 27 to March 5, 2020, were collected and analyzed, and coagulation function parameters were described and compared between patients with severe infection and those with non-severe infection. Cohort studies reporting risk estimates for the D-dimer and severity of COVID-19 association were searched and included to perform a meta-analysis. RESULTS: In our cohort study, patients with severe disease were more likely to exhibit dysregulated coagulation function, and a significantly higher D-dimer level (median 1.8 mug/ml [interquartile range 0.9-4.6] vs 0.5 [0.3-1.1], p < 0.001) was found in severe cases than the mild ones, on admission. In the meta-analysis of 13 cohort studies (including the current study), patients with severe disease had an increase in mean D-dimer value by 0.91 (95% confidence interval, 0.51-1.31, p < 0.001) mug/ml compared to those with non-severe disease, and odds of severe infection was associated with D-dimer greater than 0.5 mug/ml (odds ratio = 5.78, 95% confidence interval, 2.16-15.44, p < 0.001) on admission. CONCLUSIONS: Patients with severe COVID-19 have a higher level of D-dimer than those with non-severe disease, and D-dimer greater than 0.5 mug/ml is associated with severe infection in patients with COVID-19. Twit Text FOAVip D-dimer level is associated with the severity of COVID-19 ????Thromb Res http://www.kidney.de/pget.php?&tw=1&pmid=32777639 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32777639 #FOAvip English Wikipedia <ref>{{Cite pmid|32777639}}</ref> D-dimer level is associated with the severity of COVID-19 #MMPMID32777639 Yu HH; Qin C; Chen M; Wang W; Tian DS Thromb Res 2020[Nov]; 195 (ä): 219-225 PMID32777639show ga INTRODUCTION: Abnormal coagulation function has been demonstrated to be involved in the disease progression of COVID-19. However, the association between D-dimer levels and the severity of COVID-19 is not clear. The study was aimed to investigate the association between D-dimer levels and the severity of COVID-19 based on a cohort study and meta-analysis. MATERIALS AND METHODS: Demographic and clinical data of all confirmed cases with COVID-19 on admission to Tongji Hospital from January 27 to March 5, 2020, were collected and analyzed, and coagulation function parameters were described and compared between patients with severe infection and those with non-severe infection. Cohort studies reporting risk estimates for the D-dimer and severity of COVID-19 association were searched and included to perform a meta-analysis. RESULTS: In our cohort study, patients with severe disease were more likely to exhibit dysregulated coagulation function, and a significantly higher D-dimer level (median 1.8 mug/ml [interquartile range 0.9-4.6] vs 0.5 [0.3-1.1], p < 0.001) was found in severe cases than the mild ones, on admission. In the meta-analysis of 13 cohort studies (including the current study), patients with severe disease had an increase in mean D-dimer value by 0.91 (95% confidence interval, 0.51-1.31, p < 0.001) mug/ml compared to those with non-severe disease, and odds of severe infection was associated with D-dimer greater than 0.5 mug/ml (odds ratio = 5.78, 95% confidence interval, 2.16-15.44, p < 0.001) on admission. CONCLUSIONS: Patients with severe COVID-19 have a higher level of D-dimer than those with non-severe disease, and D-dimer greater than 0.5 mug/ml is associated with severe infection in patients with COVID-19. |Aged[MESH] |Betacoronavirus/isolation & purification[MESH] |Blood Coagulation[MESH] |COVID-19[MESH] |Cohort Studies[MESH] |Coronavirus Infections/*blood/diagnosis/epidemiology[MESH] |Female[MESH] |Fibrin Fibrinogen Degradation Products/*analysis[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/*blood/diagnosis/epidemiology[MESH] |SARS-CoV-2[MESH]D-dimer level is associated with the severity of COVID-19 (epmc).pdf DeepDyve Pubget Overpricing