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10.1016/j.jgar.2020.07.022

http://scihub22266oqcxt.onion/10.1016/j.jgar.2020.07.022
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32777441!7836824!32777441
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suck abstract from ncbi


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pmid32777441      J+Glob+Antimicrob+Resist 2020 ; 22 (ä): 864-865
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  • Why is pre-exposure prophylaxis with hydroxychloroquine a safe and rationale approach against SARS-CoV-2 infection? #MMPMID32777441
  • Mehta S; Bhandari S; Mehta S
  • J Glob Antimicrob Resist 2020[Sep]; 22 (ä): 864-865 PMID32777441show ga
  • The potentiality of Hydroxychloroquine (HCQ) for pre-exposure prophylaxis against SARS-CoV-2 has not been explored in randomized controlled trials. However, there is rationale behind this potentiality in terms of demonstrated in-vitro effect of HCQ against SARS-CoV-2, safety profile of HCQ in healthy individuals and a recent observational study demonstrating benefits of HCQ prophylaxis in terms of a significant reduction (>80%) in the odds of SARS-CoV-2 infection in the health-care workers (HCWs) with the intake of six or more doses of HCQ prophylaxis as per the guidelines of the National Task Force for COVID-19 in India. Hence, pre-exposure prophylaxis with HCQ in appears to be a reasonable strategy in the current scenario for prevention of SARS-CoV-2 infection in healthy HCWs.
  • |Antiviral Agents/*administration & dosage[MESH]
  • |Betacoronavirus/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/drug therapy/*prevention & control/virology[MESH]
  • |Health Personnel[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/*administration & dosage[MESH]
  • |India[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/*prevention & control/virology[MESH]
  • |Pre-Exposure Prophylaxis/*methods[MESH]


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