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Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Am+Acad+Dermatol 2020 ; 83 (6): 1738-1748 Nephropedia Template TP
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Review of adverse cutaneous reactions of pharmacologic interventions for COVID-19: A guide for the dermatologist #MMPMID32777318
Martinez-Lopez A; Cuenca-Barrales C; Montero-Vilchez T; Molina-Leyva A; Arias-Santiago S
J Am Acad Dermatol 2020[Dec]; 83 (6): 1738-1748 PMID32777318show ga
The new coronavirus, severe acute respiratory syndrome coronavirus 2, is associated with a wide variety of cutaneous manifestations. Although new skin manifestations caused by COVID-19 are continuously being described, other cutaneous entities should also be considered in the differential diagnosis, including adverse cutaneous reactions to drugs used in the treatment of COVID-19 infections. The aim of this review is to provide dermatologists with an overview of the cutaneous adverse effects associated with the most frequently prescribed drugs in patients with COVID-19. The skin reactions of antimalarials (chloroquine and hydroxychloroquine), antivirals (lopinavir/ritonavir, ribavirin with or without interferon, oseltamivir, remdesivir, favipiravir, and darunavir), and treatments for complications (imatinib, tocilizumab, anakinra, immunoglobulins, corticosteroids, colchicine and low molecular weight heparins) are analyzed. Information regarding possible skin reactions, their frequency, management, and key points for differential diagnosis are presented.