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10.1111/ajt.16251 http://scihub22266oqcxt.onion/10.1111/ajt.16251 32777130!7436721!32777130     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transplant 2020 ; 20 (11): 3162-3172 Nephropedia Template TP {{tp|p=32777130|t=2020. In-depth virological assessment of kidney transplant recipients with COVID-19 |pdf=|usr=}}{{32777130}} gab.com Text In-depth virological assessment of kidney transplant recipients with COVID-19 JO: Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=32777130 #FOAvip Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread widely, causing coronavirus disease 2019 (COVID-19) and significant mortality. However, data on viral loads and antibody kinetics in immunocompromised populations are lacking. We aimed to determine nasopharyngeal and plasma viral loads via reverse transcription-polymerase chain reaction and SARS-CoV-2 serology via enzyme-linked immunosorbent assay and study their association with severe forms of COVID-19 and death in kidney transplant recipients. In this study, we examined hospitalized kidney transplant recipients with nonsevere (n = 21) and severe (n = 19) COVID-19. SARS-CoV-2 nasopharyngeal and plasma viral load and serological response were evaluated based on outcomes and disease severity. Ten recipients (25%) displayed persistent viral shedding 30 days after symptom onset. The SARS-CoV-2 viral load of the upper respiratory tract was not associated with severe COVID-19, whereas the plasma viral load was associated with COVID-19 severity (P = .010) and mortality (P = .010). All patients harbored antibodies during the second week after symptom onset that persisted for 2 months. We conclude that plasma viral load is associated with COVID-19 morbidity and mortality, whereas nasopharyngeal viral load is not. SARS-CoV-2 shedding is prolonged in kidney transplant recipients and the humoral response to SARS-CoV-2 does not show significant impairment in this series of transplant recipients. Twit Text FOAVip In-depth virological assessment of kidney transplant recipients with COVID-19 ????Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=32777130 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32777130 #FOAvip English Wikipedia <ref>{{Cite pmid|32777130}}</ref> In-depth virological assessment of kidney transplant recipients with COVID-19 #MMPMID32777130 Benotmane I; Gautier-Vargas G; Wendling MJ; Perrin P; Velay A; Bassand X; Bedo D; Baldacini C; Sagnard M; Bozman DF; Della-Chiesa M; Solis M; Gallais F; Cognard N; Olagne J; Delagreverie H; Gontard L; Panaget B; Marx D; Heibel F; Braun-Parvez L; Moulin B; Caillard S; Fafi-Kremer S Am J Transplant 2020[Nov]; 20 (11): 3162-3172 PMID32777130show ga Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread widely, causing coronavirus disease 2019 (COVID-19) and significant mortality. However, data on viral loads and antibody kinetics in immunocompromised populations are lacking. We aimed to determine nasopharyngeal and plasma viral loads via reverse transcription-polymerase chain reaction and SARS-CoV-2 serology via enzyme-linked immunosorbent assay and study their association with severe forms of COVID-19 and death in kidney transplant recipients. In this study, we examined hospitalized kidney transplant recipients with nonsevere (n = 21) and severe (n = 19) COVID-19. SARS-CoV-2 nasopharyngeal and plasma viral load and serological response were evaluated based on outcomes and disease severity. Ten recipients (25%) displayed persistent viral shedding 30 days after symptom onset. The SARS-CoV-2 viral load of the upper respiratory tract was not associated with severe COVID-19, whereas the plasma viral load was associated with COVID-19 severity (P = .010) and mortality (P = .010). All patients harbored antibodies during the second week after symptom onset that persisted for 2 months. We conclude that plasma viral load is associated with COVID-19 morbidity and mortality, whereas nasopharyngeal viral load is not. SARS-CoV-2 shedding is prolonged in kidney transplant recipients and the humoral response to SARS-CoV-2 does not show significant impairment in this series of transplant recipients. |*Kidney Transplantation[MESH] |*Pandemics[MESH] |*Viral Load[MESH] |Aged[MESH] |Antibodies, Viral/*immunology[MESH] |COVID-19/epidemiology/*virology[MESH] |Comorbidity[MESH] |Enzyme-Linked Immunosorbent Assay[MESH] |Female[MESH] |France/epidemiology[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Nasopharynx/virology[MESH] |SARS-CoV-2/*immunology[MESH]In-depth virological assessment of kidney transplant recipients with C(epmc).pdf DeepDyve Pubget Overpricing