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10.1002/jmv.26404

http://scihub22266oqcxt.onion/10.1002/jmv.26404
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32776581!7436524!32776581
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suck abstract from ncbi


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pmid32776581      J+Med+Virol 2021 ; 93 (2): 1099-1104
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  • The outcome of COVID-19 in patients with hematological malignancy #MMPMID32776581
  • Yigenoglu TN; Ata N; Altuntas F; Basci S; Dal MS; Korkmaz S; Namdaroglu S; Basturk A; Hacibekiroglu T; Dogu MH; Berber I; Dal K; Erkurt MA; Turgut B; Ulgu MM; Celik O; Imrat E; Birinci S
  • J Med Virol 2021[Feb]; 93 (2): 1099-1104 PMID32776581show ga
  • In this study, we aim to report the outcomes for COVID-19 in patients with hematological malignancy in Turkey. Data from laboratory-confirmed 188 897 COVID-19 patients diagnosed between 11 March 2020 and 22 June 2020 included in the Republic of Turkey, Ministry of Health database were analyzed retrospectively. All COVID-19 patients with hematological malignancy (n = 740) were included in the study and an age, sex, and comorbidity-matched cohort of COVID-19 patients without cancer (n = 740) at a 1:1 ratio was used for comparison. Non-Hodgkin lymphoma (30.1%), myelodysplastic syndrome (19.7%), myeloproliferative neoplasm (15.7%) were the most common hematological malignancies. The rates of severe and critical disease were significantly higher in patients with hematological malignancy compared with patients without cancer (P = .001). The rates of hospital and intensive care unit (ICU) admission were higher in patients with hematological malignancy compared with the patients without cancer (P = .023, P = .001, respectively). The length of hospital stay and ICU stay was similar between groups (P = .7, P = .3, retrospectively). The rate of mechanical ventilation (MV) support was higher in patients with hematological malignancy compared with the control group (P = .001). The case fatality rate was 13.8% in patients with hematological malignancy, and it was 6.8% in the control group (P = .001). This study reveals that there is an increased risk of COVID-19-related serious events (ICU admission, MV support, or death) in patients with hematological malignancy compared with COVID-19 patients without cancer and confirms the high vulnerability of patients with hematological malignancy in the current pandemic.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*epidemiology/*physiopathology[MESH]
  • |Comorbidity[MESH]
  • |Female[MESH]
  • |Hematologic Neoplasms/*complications/epidemiology/*virology[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Length of Stay/statistics & numerical data[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Respiration, Artificial/statistics & numerical data[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |Turkey/epidemiology[MESH]


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