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10.4097/kja.20327 http://scihub22266oqcxt.onion/10.4097/kja.20327 32773727!8342838!32773727     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Korean+J+Anesthesiol 2021 ; 74 (4): 350-354 Nephropedia Template TP {{tp|p=32773727|t=2021. Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry -two case reports |pdf=|usr=}}{{32773727}} gab.com Text Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry -two case reports JO: Korean J Anesthesiol http://www.kidney.de/pget.php?&tw=1&pmid=32773727 #FOAvip BACKGROUND: Coronavirus disease (COVID-19)-associated coagulopathy is most often characterized by elevated D-dimer, interleukin-6, and plasma fibrinogen concentrations as well as hypercoagulability in thromboelastometry with increased clot firmness in the EXTEM, INTEM, and FIBTEM assays. Clinically, it manifests with a very high incidence of thrombosis, particularly in the pulmonary system, whereas bleeding complications are infrequent. CASE: Here, we describe two critically ill patients with COVID-19 admitted to our intensive care unit demonstrating different thromboelastometry and biomarker patterns. One patient presented with hypercoagulability and the other patient with hypocoagulability and fibrinolysis shutdown in thromboelastometry. The pathophysiology and the potential impact on treatment options are discussed. CONCLUSIONS: A combination of biomarkers and thromboelastometry results can be helpful in the future to decide which therapeutic strategy might be most appropriate for critically ill patients with COVID-19. This would be an important step to establish precision medicine in this high-risk patient population. Twit Text FOAVip Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry -two case reports ????Korean J Anesthesiol http://www.kidney.de/pget.php?&tw=1&pmid=32773727 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32773727 #FOAvip English Wikipedia <ref>{{Cite pmid|32773727}}</ref> Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry -two case reports #MMPMID32773727 Kong R; Hutchinson N; Gorlinger K Korean J Anesthesiol 2021[Aug]; 74 (4): 350-354 PMID32773727show ga BACKGROUND: Coronavirus disease (COVID-19)-associated coagulopathy is most often characterized by elevated D-dimer, interleukin-6, and plasma fibrinogen concentrations as well as hypercoagulability in thromboelastometry with increased clot firmness in the EXTEM, INTEM, and FIBTEM assays. Clinically, it manifests with a very high incidence of thrombosis, particularly in the pulmonary system, whereas bleeding complications are infrequent. CASE: Here, we describe two critically ill patients with COVID-19 admitted to our intensive care unit demonstrating different thromboelastometry and biomarker patterns. One patient presented with hypercoagulability and the other patient with hypocoagulability and fibrinolysis shutdown in thromboelastometry. The pathophysiology and the potential impact on treatment options are discussed. CONCLUSIONS: A combination of biomarkers and thromboelastometry results can be helpful in the future to decide which therapeutic strategy might be most appropriate for critically ill patients with COVID-19. This would be an important step to establish precision medicine in this high-risk patient population. |Aged[MESH] |Blood Coagulation Disorders/*complications/*diagnosis/pathology[MESH] |COVID-19/*complications[MESH] |Fatal Outcome[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |SARS-CoV-2[MESH] |Thrombelastography/*methods[MESH]Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastom(epmc).pdf DeepDyve Pubget Overpricing