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10.4103/ijmr.IJMR_1788_20

http://scihub22266oqcxt.onion/10.4103/ijmr.IJMR_1788_20
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suck abstract from ncbi


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pmid32773414      Indian+J+Med+Res 2020 ; 152 (1 & 2): 61-69
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  • Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India #MMPMID32773414
  • Mohan A; Tiwari P; Bhatnagar S; Patel A; Maurya A; Dar L; Pahuja S; Garg R; Gupta N; Sahoo B; Gupta R; Meena VP; Vig S; Pandit A; Mittal S; Madan K; Hadda V; Dwivedi T; Choudhary A; Brijwal M; Soneja M; Guleria R; Ratre B; Kumar B; Bhopale S; Panda S; Singh AR; Singh S; Wundavalli L
  • Indian J Med Res 2020[Jul]; 152 (1 & 2): 61-69 PMID32773414show ga
  • BACKGROUND & OBJECTIVES: In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations and outcomes of this disease (COVID-19) have been reported from different countries. The present study was aimed to describe the clinico-demographic characteristics and in-hospital outcomes of a group of COVID-19 patients in north India. METHODS: This was a prospective, single-centre collection of data regarding epidemiological, demographic, clinical and laboratory parameters, management and outcome of COVID-19 patients admitted in a tertiary care facility in north India. Patient outcomes were recorded as death, discharge and still admitted. RESULTS: Data of 144 patients with COVID-19 were recorded and analyzed. The mean age of the patients was 40.1+/-13.1 yr, with 93.1 per cent males, and included 10 (6.9%) foreign nationals. Domestic travel to or from affected States (77.1%) and close contact with COVID-19 patients in congregations (82.6%) constituted the most commonly documented exposure. Nine (6.3%) patients were smokers, with a median smoking index of 200. Comorbidities were present in 23 (15.9%) patients, of which diabetes mellitus (n=16; 11.1%) was the most common. A significant proportion of patients had no symptoms (n=64; 44.4%); among the symptomatic, cough (34.7%) was the most common symptom followed by fever (17.4%) and nasal symptoms (2.15%). Majority of the patients were managed with supportive treatment with hydroxychloroquine and azithromycin given on a case-to-case basis. Only five (3.5%) patients required oxygen supplementation, four (2.8%) patients had severe disease requiring intensive care, one required mechanical ventilation and mortality occurred in two (1.4%) patients. The time to reverse transcription-polymerase chain reaction (RT-PCR) negativity was 16-18 days. INTERPRETATION & CONCLUSIONS: In this single-centre study of 144 hospitalized patients with confirmed COVID-19 in north India, the characteristic findings included younger age, high proportion of asymptomatic patients, long time to PCR negativity and low need for intensive care unit care.
  • |*Tertiary Care Centers[MESH]
  • |Adult[MESH]
  • |Betacoronavirus/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*epidemiology/pathology/therapy/virology[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Hospitals[MESH]
  • |Humans[MESH]
  • |India/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/pathology/therapy/virology[MESH]


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