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10.1016/j.ejmech.2020.112687 http://scihub22266oqcxt.onion/10.1016/j.ejmech.2020.112687 32771797!7385720!32771797     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Med+Chem 2020 ; 205 (ä): 112687 Nephropedia Template TP {{tp|p=32771797|t=2020. Potential treatment methods targeting 2019-nCoV infection |pdf=|usr=}}{{32771797}} gab.com Text Potential treatment methods targeting 2019-nCoV infection JO: Eur J Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=32771797 #FOAvip The novel coronavirus, 2019-nCoV, has quickly spread across the world and pose serious threat to public health because it can infect people very easily. The major clinical symptoms of 2019-nCoV infection include fever, dry cough, myalgia, fatigue, and diarrhea. The 2019-nCoV belongs to the betacoronavirus family, and gene sequencing results demonstrate that it is a single-stranded RNA virus, closely related to Severe Acute Respiratory Syndrome CoV (SARS-CoV) and Middle East Respiratory Syndrome CoV (MERS-CoV). It has been observed that the virus invades human body mainly through binding to angiotensin-converting enzyme 2 (ACE2) receptors similar to SARS-CoV and the main protease (Mpro) acts as a critical protease for digesting the polyprotein into functional polypeptides during the replication and transcription process of 2019-nCoV. In this review, we summarized the real-time information of 2019-nCoV treatment methods and mainly focused on the chemical drugs including lopinavir/ritonavir, chloroquine, hydroxychloroquine, arbidol, remdesivir, favipiravir and other potential innovative active molecules. Their potential targets, activity, clinical status and side effects are described. In addition, Traditional Chinese Medicine (TCM), Convalescent plasma therapy (CPT) and biological reagents available, as well as the promising vaccine candidates against 2019-nCoV are also discussed. Twit Text FOAVip Potential treatment methods targeting 2019-nCoV infection ????Eur J Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=32771797 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32771797 #FOAvip English Wikipedia <ref>{{Cite pmid|32771797}}</ref> Potential treatment methods targeting 2019-nCoV infection #MMPMID32771797 Zheng L; Zhang L; Huang J; Nandakumar KS; Liu S; Cheng K Eur J Med Chem 2020[Nov]; 205 (ä): 112687 PMID32771797show ga The novel coronavirus, 2019-nCoV, has quickly spread across the world and pose serious threat to public health because it can infect people very easily. The major clinical symptoms of 2019-nCoV infection include fever, dry cough, myalgia, fatigue, and diarrhea. The 2019-nCoV belongs to the betacoronavirus family, and gene sequencing results demonstrate that it is a single-stranded RNA virus, closely related to Severe Acute Respiratory Syndrome CoV (SARS-CoV) and Middle East Respiratory Syndrome CoV (MERS-CoV). It has been observed that the virus invades human body mainly through binding to angiotensin-converting enzyme 2 (ACE2) receptors similar to SARS-CoV and the main protease (Mpro) acts as a critical protease for digesting the polyprotein into functional polypeptides during the replication and transcription process of 2019-nCoV. In this review, we summarized the real-time information of 2019-nCoV treatment methods and mainly focused on the chemical drugs including lopinavir/ritonavir, chloroquine, hydroxychloroquine, arbidol, remdesivir, favipiravir and other potential innovative active molecules. Their potential targets, activity, clinical status and side effects are described. In addition, Traditional Chinese Medicine (TCM), Convalescent plasma therapy (CPT) and biological reagents available, as well as the promising vaccine candidates against 2019-nCoV are also discussed. |Antiviral Agents/*therapeutic use[MESH] |COVID-19[MESH] |COVID-19 Serotherapy[MESH] |Coronavirus Infections/*drug therapy/therapy[MESH] |Humans[MESH] |Immunization, Passive[MESH] |Immunotherapy/methods[MESH] |Medicine, Chinese Traditional[MESH] |Pandemics[MESH]Potential treatment methods targeting 2019-nCoV infection (epmc).pdf DeepDyve Pubget Overpricing