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10.1002/iid3.337

http://scihub22266oqcxt.onion/10.1002/iid3.337
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32770646!7436537!32770646
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suck abstract from ncbi


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pmid32770646      Immun+Inflamm+Dis 2020 ; 8 (4): 534-543
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  • A family cluster of diagnosed coronavirus disease 2019 (COVID-19) kidney transplant recipient in Thailand #MMPMID32770646
  • Sakulkonkij P; Bruminhent J; Pankongngam C; Chalermphunchai N
  • Immun Inflamm Dis 2020[Dec]; 8 (4): 534-543 PMID32770646show ga
  • INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes an ongoing outbreak of respiratory illness called coronavirus disease 2019 (COVID-19). The clinical course could be ranging from mild to severe illness especially the individuals with an immunocompromised condition such as solid organ transplant recipients. METHOD: We described a family cluster of COVID-19 patients who were admitted during 3rd April 2020 to 30th April 2020. COVID-19 was confirmed by a presence of SARS-CoV-2 ribonucleic acid in the respiratory specimens detected by a qualitative, real-time reverse transcription-polymerase chain reaction. The study focused on the clinical course and management of our cases. RESULTS: A family cluster of four laboratory-confirmed COVID-19 patients, one of those carried an underlying kidney transplant (KT) receiving immunosuppressants. Clinical presentation and severity of our case series are variable depending on each individual immune status. By far, a KT recipient seems to develop more severity despite antiviral therapy, cessation of immunosuppressant, and aggressive intensive care support. CONCLUSION: Our case series plausibly affirmed a person-to-person transmission and potentially severe disease in the transplant population. Clinicians who are encountering with transplant recipients should be aware of possible transmission among family members.
  • |Adult[MESH]
  • |Betacoronavirus/*immunology/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/diagnosis/*immunology/transmission/virology[MESH]
  • |Family[MESH]
  • |Female[MESH]
  • |Graft Rejection/etiology/immunology/*prevention & control[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/adverse effects[MESH]
  • |Kidney Transplantation/*adverse effects[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*immunology/transmission/virology[MESH]
  • |Radiography[MESH]
  • |SARS-CoV-2[MESH]


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