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10.1097/MD.0000000000021570

http://scihub22266oqcxt.onion/10.1097/MD.0000000000021570
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32769902!7593078!32769902
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suck abstract from ncbi


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pmid32769902      Medicine+(Baltimore) 2020 ; 99 (32): e21570
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  • Macrophage activation syndrome as an unusual presentation of paucisymptomatic severe acute respiratory syndrome coronavirus 2 infection: A case report #MMPMID32769902
  • Lolachi S; Morin S; Coen M; Samii K; Calmy A; Serratrice J
  • Medicine (Baltimore) 2020[Aug]; 99 (32): e21570 PMID32769902show ga
  • RATIONALE: Macrophage activation syndrome (MAS) is a rare life-threatening condition characterized by cytokine-mediated tissue injury and multiorgan dysfunction. PATIENT CONCERNS: We describe the unique case of young man who developed MAS as the sole manifestation of an otherwise paucisymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. DIAGNOSES: Clinical and biological criteria led to the diagnosis of MAS; cytokine profile was highly suggestive reverse transcription polymerase chain reaction for SARS-CoV-2 in nasopharyngeal swabs was negative, but serum anti-SARS-CoV-2 immunoglobulin A and immunoglobulin G resulted positive leading to the diagnosis of SARS-CoV-2 infection. INTERVENTIONS: The patient was treated with empiric antibiotic and hydroxychloroquine. OUTCOMES: Clinical improvement ensued. At follow-up, the patient is well. LESSON: SARS-CoV-2 infection may trigger develop life-threatening complications, like MAS. This can be independent from coronavirus disease 2019 gravity.
  • |*Hospitalization[MESH]
  • |Adolescent[MESH]
  • |Blood Chemical Analysis[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Ceftriaxone/*administration & dosage[MESH]
  • |China[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Coronavirus Infections/*diagnosis/drug therapy[MESH]
  • |DNA, Viral/analysis[MESH]
  • |Diagnosis, Differential[MESH]
  • |Disease Progression[MESH]
  • |Drug Therapy, Combination[MESH]
  • |Electrocardiography/methods[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/*administration & dosage[MESH]
  • |Macrophage Activation Syndrome/*diagnosis/therapy[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Patient Discharge[MESH]
  • |Pneumonia, Viral/*diagnosis/drug therapy[MESH]
  • |Radiography, Thoracic/methods[MESH]
  • |Real-Time Polymerase Chain Reaction/methods[MESH]
  • |Risk Assessment[MESH]
  • |Severity of Illness Index[MESH]
  • |Tomography, X-Ray Computed/methods[MESH]


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