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10.26355/eurrev_202008_22507

http://scihub22266oqcxt.onion/10.26355/eurrev_202008_22507
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32767348!ä!32767348

suck abstract from ncbi


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pmid32767348      Eur+Rev+Med+Pharmacol+Sci 2020 ; 24 (15): 8187-8193
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  • Inhibitory effects of Vitamin D on inflammation and IL-6 release A further support for COVID-19 management? #MMPMID32767348
  • Orru B; Szekeres-Bartho J; Bizzarri M; Spiga AM; Unfer V
  • Eur Rev Med Pharmacol Sci 2020[Aug]; 24 (15): 8187-8193 PMID32767348show ga
  • The ongoing worldwide pandemic of Coronavirus disease 2019 (COVID-19), raised the urgency to address knowledge gaps and to establish evidence for improving management and control of this viral infection. Throughout a keen analysis of the World Health Organization (WHO) most updated data, a gender-specific difference in the occurrence of infection was determined, which seems to correlate with patient's vitamin D status. Therefore, our purpose is to provide insights into the nutritional importance of vitamin D for its immunomodulatory effect, in order to help counteracting the COVID-19 pandemic. Novel interesting findings suggest that vitamin D, by inducing progesterone-induced blocking factor (PIBF), might regulate the immune response and also modulate cytokine IL-6, which appears to be increased in COVID-19 infections. Therefore, in addition to the standard recommendations to prevent the infection, supplementation of vitamin D might be considered an approach to help counteracting this global epidemic.
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/drug therapy/epidemiology/*immunology/prevention & control[MESH]
  • |Geography[MESH]
  • |Humans[MESH]
  • |Inflammation[MESH]
  • |Interleukin-6/*immunology[MESH]
  • |Italy/epidemiology[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Pneumonia, Viral/epidemiology/*immunology/prevention & control[MESH]
  • |Pregnancy Proteins/*immunology[MESH]
  • |SARS-CoV-2[MESH]
  • |Suppressor Factors, Immunologic/*immunology[MESH]
  • |Ultraviolet Rays[MESH]
  • |Vitamin D Deficiency/*drug therapy/immunology[MESH]
  • |Vitamin D/*immunology/*therapeutic use[MESH]


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