Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1101/2020.07.27.224063 http://scihub22266oqcxt.onion/10.1101/2020.07.27.224063 32766585!7402042!32766585     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       bioRxiv 2020 ; ä (ä): ä Nephropedia Template TP {{tp|p=32766585|t=2020. Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories |pdf=|usr=}}{{32766585}} gab.com Text Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories JO: bioRxiv http://www.kidney.de/pget.php?&tw=1&pmid=32766585 #FOAvip Host immune responses play central roles in controlling SARS-CoV2 infection, yet remain incompletely characterized and understood. Here, we present a comprehensive immune response map spanning 454 proteins and 847 metabolites in plasma integrated with single-cell multi-omic assays of PBMCs in which whole transcriptome, 192 surface proteins, and T and B cell receptor sequence were co-analyzed within the context of clinical measures from 50 COVID19 patient samples. Our study reveals novel cellular subpopulations, such as proliferative exhausted CD8 (+) and CD4 (+) T cells, and cytotoxic CD4 (+) T cells, that may be features of severe COVID-19 infection. We condensed over 1 million immune features into a single immune response axis that independently aligns with many clinical features and is also strongly associated with disease severity. Our study represents an important resource towards understanding the heterogeneous immune responses of COVID-19 patients and may provide key information for informing therapeutic development. Twit Text FOAVip Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories ????bioRxiv http://www.kidney.de/pget.php?&tw=1&pmid=32766585 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32766585 #FOAvip English Wikipedia <ref>{{Cite pmid|32766585}}</ref> Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories #MMPMID32766585 Su Y; Chen D; Lausted C; Yuan D; Choi J; Dai C; Voillet V; Scherler K; Troisch P; Duvvuri VR; Baloni P; Qin G; Smith B; Kornilov S; Rostomily C; Xu A; Li J; Dong S; Rothchild A; Zhou J; Murray K; Edmark R; Hong S; Jones L; Zhou Y; Roper R; Mackay S; O'Mahony DS; Dale CR; Wallick JA; Algren HA; Michael ZA; Magis A; Wei W; Price ND; Huang S; Subramanian N; Wang K; Hadlock J; Hood L; Aderem A; Bluestone JA; Lanier LL; Greenberg P; Gottardo R; Davis MM; Goldman JD; Heath JR bioRxiv 2020[Jul]; ä (ä): ä PMID32766585show ga Host immune responses play central roles in controlling SARS-CoV2 infection, yet remain incompletely characterized and understood. Here, we present a comprehensive immune response map spanning 454 proteins and 847 metabolites in plasma integrated with single-cell multi-omic assays of PBMCs in which whole transcriptome, 192 surface proteins, and T and B cell receptor sequence were co-analyzed within the context of clinical measures from 50 COVID19 patient samples. Our study reveals novel cellular subpopulations, such as proliferative exhausted CD8 (+) and CD4 (+) T cells, and cytotoxic CD4 (+) T cells, that may be features of severe COVID-19 infection. We condensed over 1 million immune features into a single immune response axis that independently aligns with many clinical features and is also strongly associated with disease severity. Our study represents an important resource towards understanding the heterogeneous immune responses of COVID-19 patients and may provide key information for informing therapeutic development. äMultiomic Immunophenotyping of COVID-19 Patients Reveals Early Infecti(epmc).pdf DeepDyve Pubget Overpricing