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10.1136/oemed-2020-106676

http://scihub22266oqcxt.onion/10.1136/oemed-2020-106676
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32764107!ä!32764107

suck abstract from ncbi


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pmid32764107      Occup+Environ+Med 2020 ; 77 (12): 857-861
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  • Epidemiology of SARS-CoV-2 antibodies among firefighters/paramedics of a US fire department: a cross-sectional study #MMPMID32764107
  • Caban-Martinez AJ; Schaefer-Solle N; Santiago K; Louzado-Feliciano P; Brotons A; Gonzalez M; Issenberg SB; Kobetz E
  • Occup Environ Med 2020[Dec]; 77 (12): 857-861 PMID32764107show ga
  • OBJECTIVES: We estimate the point seroprevalence of SARS-CoV-2 antibodies in the frontline firefighter/paramedic workforce of a South Florida fire department located in the epicentre of a State outbreak. METHODS: A cross-sectional study design was used to estimate the point seroprevalence of SARS-CoV-2 antibodies using a rapid immunoglobulin (Ig)M-IgG combined point-of-care lateral flow immunoassay among frontline firefighters/paramedics collected over a 2-day period, 16-17 April 2020. Fire department personnel were emailed a survey link assessing COVID-19 symptoms and work exposures the day prior to the scheduled drive-through antibody testing at a designated fire station. Off-duty and on-duty firefighter/paramedic personnel drove through the fire station/training facility in their personal vehicles or on-duty engine/rescue trucks for SARS-CoV-2 antibody testing. RESULTS: Among the 203 firefighters/paramedics that make up the fire department workforce, 18 firefighters/paramedics (8.9%) tested positive for SARS-CoV-2 antibodies, of which 8 firefighters/paramedics (3.9%) were IgG positive only, 8 (3.9%) were IgM positive only and 2 (0.1%) were IgG/IgM positive. The positive predictive value (PPV) of the serological test is estimated to be 33.2% and the negative predictive value is 99.3%. The average number of COVID-19 case contacts (ie, within 6 feet of an infected person (laboratory-confirmed or probable COVID-19 patient) for >/=15 min) experienced by firefighters/paramedics was higher for those with positive serology compared with those with negative (13.3 cases vs 7.31 cases; p=0.022). None of the antibody positive firefighters/paramedics reported receipt of the annual influenza vaccine compared with firefighters/paramedics who tested negative for SARS-CoV-2 antibodies (0.0% vs 21.0%; p=0.027). CONCLUSION: Rapid SARS-CoV-2 IgM-IgG antibody testing documented early-stage and late-stage infection in a firefighter workforce providing insight to a broader medical surveillance project on return to work for firefighters/paramedics. Given the relatively low PPV of the serological test used in this study back in April 2020, caution should be used in interpreting test results.
  • |*Allied Health Personnel[MESH]
  • |*Firefighters[MESH]
  • |*Occupational Exposure[MESH]
  • |Adult[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |Betacoronavirus/*immunology[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Coronavirus Infections/blood/diagnosis/*epidemiology/virology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Disease Outbreaks[MESH]
  • |Female[MESH]
  • |Florida/epidemiology[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/*blood[MESH]
  • |Immunoglobulin M/*blood[MESH]
  • |Influenza Vaccines[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/blood/diagnosis/*epidemiology/virology[MESH]
  • |Population Surveillance[MESH]
  • |Prevalence[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Seroepidemiologic Studies[MESH]
  • |Workplace[MESH]


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