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10.1016/j.msard.2020.102437

http://scihub22266oqcxt.onion/10.1016/j.msard.2020.102437
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32763844!7392845!32763844
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suck abstract from ncbi


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pmid32763844      Mult+Scler+Relat+Disord 2020 ; 45 (ä): 102437
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  • The multiple sclerosis (MS) drugs as a potential treatment of ARDS in COVID-19 patients #MMPMID32763844
  • Kloc M; Ghobrial RM
  • Mult Scler Relat Disord 2020[Oct]; 45 (ä): 102437 PMID32763844show ga
  • We encourage studies on the effectiveness of multiple sclerosis drugs for the treatment of ARDS in COVID-19 infection. These drugs, through the inhibition of the RhoA/actin-dependent expression of virus receptors in the macrophages and macrophage recruitment to the lungs, have the potential to inhibit cytokine storm of lung macrophages, reduce or eliminate ARDS and improve the outcome of COVID-19 infection.
  • |Azetidines/therapeutic use[MESH]
  • |Benzyl Compounds/therapeutic use[MESH]
  • |Betacoronavirus/drug effects[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/complications/*drug therapy[MESH]
  • |Enzyme Inhibitors/*therapeutic use[MESH]
  • |Fingolimod Hydrochloride/therapeutic use[MESH]
  • |Humans[MESH]
  • |Multiple Sclerosis/drug therapy[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/*drug therapy[MESH]
  • |Respiratory Distress Syndrome/*drug therapy/virology[MESH]
  • |SARS-CoV-2[MESH]


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