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10.1016/j.rce.2020.07.003

http://scihub22266oqcxt.onion/10.1016/j.rce.2020.07.003
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32762922!7480740!32762922
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suck abstract from ncbi


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pmid32762922      Rev+Clin+Esp+(Barc) 2020 ; 220 (8): 480-494
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  • Caracteristicas clinicas de los pacientes hospitalizados con COVID-19 en Espana: resultados del Registro SEMI-COVID-19 #MMPMID32762922
  • Casas-Rojo JM; Anton-Santos JM; Millan-Nunez-Cortes J; Lumbreras-Bermejo C; Ramos-Rincon JM; Roy-Vallejo E; Artero-Mora A; Arnalich-Fernandez F; Garcia-Brunen JM; Vargas-Nunez JA; Freire-Castro SJ; Manzano-Espinosa L; Perales-Fraile I; Crestelo-Vieitez A; Puchades-Gimeno F; Rodilla-Sala E; Solis-Marquinez MN; Bonet-Tur D; Fidalgo-Moreno MP; Fonseca-Aizpuru EM; Carrasco-Sanchez FJ; Rabadan-Pejenaute E; Rubio-Rivas M; Torres-Pena JD; Gomez-Huelgas R
  • Rev Clin Esp (Barc) 2020[Nov]; 220 (8): 480-494 PMID32762922show ga
  • BACKGROUND: Spain has been one of the countries most affected by the COVID-19 pandemic. OBJECTIVE: To create a registry of patients with COVID-19 hospitalized in Spain, in order to improve our knowledge of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease. METHODS: A multicentre retrospective cohort study, including consecutive patients hospitalized with confirmed COVID-19 throughout Spain. Epidemiological and clinical data, additional tests at admission and at seven days, treatments administered, and progress at 30 days of hospitalization were collected from electronic medical records. RESULTS: Up to June 30th 2020, 15,111 patients from 150 hospitals were included. Their median age was 69.4 years (range: 18-102 years) and 57.2% were male. Prevalences of hypertension, dyslipidemia, and diabetes mellitus were 50.9%, 39.7%, and 19.4%, respectively. The most frequent symptoms were fever (84.2%) and cough (73.5%). High values of ferritin (73.5%), lactate dehydrogenase (73.9%), and D-dimer (63.8%), as well as lymphopenia (52.8%), were frequent. The most used antiviral drugs were hydroxychloroquine (85.6%) and lopinavir/ritonavir (61.4%); 33.1% developed respiratory distress. Overall mortality rate was 21.0%, with a marked increase with age (50-59 years: 4.7%, 60-69 years: 10.5%, 70-79 years: 26.9%, >/=80 years: 46.0%). CONCLUSIONS: The SEMI-COVID-19 Network provides data on the clinical characteristics of patients with COVID-19 hospitalized in Spain. Patients with COVID-19 hospitalized in Spain are mostly severe cases, as one in three patients developed respiratory distress and one in five patients died. These findings confirm a close relationship between advanced age and mortality.
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