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10.1111/ene.14466

http://scihub22266oqcxt.onion/10.1111/ene.14466
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32761999!7436672!32761999
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suck abstract from ncbi


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pmid32761999      Eur+J+Neurol 2020 ; 27 (11): 2308-2311
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  • Large vessel stroke in six patients following SARS-CoV-2 infection: a retrospective case study series of acute thrombotic complications on stable underlying atherosclerotic disease #MMPMID32761999
  • Lapergue B; Lyoubi A; Meseguer E; Avram I; Denier C; Venditti L; Consoli A; Guedon A; Houdart E; Weisenburger-Lile D; Piotin M; Maier B; Obadia M; Broucker TDE
  • Eur J Neurol 2020[Nov]; 27 (11): 2308-2311 PMID32761999show ga
  • BACKGROUND AND PURPOSE: Ischaemic stroke has been described in association with COVID-19. Several pathophysiological mechanisms have been suggested, i.e. prothrombotic state, cardiac injury etc. It was sought to assess the potential association between ischaemic stroke associated with SARS-CoV-2 infection and underlying atherosclerotic lesions. METHODS: A retrospective analysis of stroke related to large vessel occlusion was conducted amongst patients with SARS-CoV-2 infection and underlying mild atherosclerotic disease, between 19 March and 19 April 2020 in six different stroke centers in the Ile-de France area, France. RESULTS: The median age was 52 years, median body mass index was 29.5 kg/m(2) . All patients displayed previous vascular risk factors such as high blood pressure, diabetes, dyslipidemia or body mass index > 25. The delay between the first respiratory symptoms of COVID-19 and stroke was 11.5 days. At baseline, all had tandem occlusions, i.e. intracerebral and extracerebral thrombus assessed with computed tomography or magnetic resonance imaging. Cases displayed a large thrombus in the cervical carotid artery with underlying mild non-stenosing atheroma, after an etiological workup based on angio-computed tomography or magnetic resonance imaging and/or cervical echography. CONCLUSION: Our study should alert clinicians to scrutinize any new onset of ischaemic stroke during COVID-19 infection, mainly in patients with vascular risk factors or underlying atherosclerotic lesions.
  • |Arterial Occlusive Diseases/etiology[MESH]
  • |Atherosclerosis/*complications/diagnostic imaging[MESH]
  • |COVID-19/*complications/diagnostic imaging[MESH]
  • |Carotid Artery Diseases/diagnostic imaging/etiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Intracranial Thrombosis/complications/diagnostic imaging/*etiology[MESH]
  • |Ischemic Stroke/diagnostic imaging/*etiology[MESH]
  • |Magnetic Resonance Imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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