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Impact of COVID-19 outbreak in reperfusion therapies of acute ischaemic stroke in northwest Spain #MMPMID32761981
Tejada Meza H; Lambea Gil A; Sancho Saldana A; Martinez-Zabaleta M; Garmendia Lopetegui E; Lopez-Cancio Martinez E; Castanon Apilanez M; Herrera Isasi M; Marta Enguita J; Gomez-Vicente B; Arenillas JF; Arenaza Basterrechea N; Timiraos Fernandez JJ; Sanchez Herrero J; Macineiras Montero JL; Castellanos Rodrigo M; Fernandez-Coud D; Casado Menendez I; Temprano Fernandez MT; Freijo M; Luna A; Palacio Portilla EJ; Jimenez Lopez Y; Rodriguez-Castro E; Rodriguez-Yanez M; Tejada Garcia J; Beltran Rodriguez I; Julian-Villaverde F; Moreno Garcia MP; Trejo Gabriel-Galan JM; Echavarria Iniguez A; Perez Lazaro C; Navarro Perez MP; Marta Moreno J
Eur J Neurol 2020[Dec]; 27 (12): 2491-2498 PMID32761981show ga
BACKGROUND AND PURPOSE: Spain has been one of the countries more heavily stricken by SARS-CoV-2, which has had huge implications for stroke care. The aim was to analyse the impact of the COVID-19 epidemic outbreak on reperfusion therapies for acute ischaemic stroke in the northwest of Spain. METHODS: This was a Spanish multicentre retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. All patients receiving reperfusion therapy for ischaemic stroke between 30 December 2019 and 3 May 2020 were recorded, and their baseline, clinical and radiological characteristics, extra- and intra-hospital times of action, Code Stroke activation pathway, COVID-19 status, reperfusion rate, and short-term outcome before and after the setting of the emergency state were analysed. RESULTS: A total of 796 patients received reperfusion therapies for ischaemic stroke. There was a decrease in the number of patients treated per week (46.5 patients per week vs. 39.0 patients per week, P = 0.043) and a delay in out-of-hospital (95.0 vs. 110.0 min, P = 0.001) and door-to-needle times (51.0 vs. 55.0, P = 0.038). Patients receiving endovascular therapy obtained less successful reperfusion rates (92.9% vs. 86.6%, P = 0.016). COVID-19 patients had more in-hospital mortality. CONCLUSION: A decrease in the number of patients benefiting from reperfusion therapies was found, with a delay in out-of-hospital and door-to-needle times and worse reperfusion rates in northwest Spain. COVID-19 patients had more in-hospital mortality.
|*COVID-19[MESH]
|*Pandemics[MESH]
|*Reperfusion[MESH]
|Adult[MESH]
|Aged[MESH]
|Aged, 80 and over[MESH]
|Emergency Medical Services/statistics & numerical data[MESH]
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Eur+J+Neurol 2020 ; 27 (12): 2491-2498
