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10.1292/jvms.20-0313 http://scihub22266oqcxt.onion/10.1292/jvms.20-0313 32759577!7653326!32759577     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Vet+Med+Sci 2020 ; 82 (10): 1410-1414 Nephropedia Template TP {{tp|p=32759577|t=2020. Role of cytotoxic T lymphocytes and interferon-gamma in coronavirus infection: Lessons from murine coronavirus infections in mice |pdf=|usr=}}{{32759577}} gab.com Text Role of cytotoxic T lymphocytes and interferon-gamma in coronavirus infection: Lessons from murine coronavirus infections in mice JO: J Vet Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=32759577 #FOAvip Murine coronavirus (CoV) is a beta-CoV that infects mice by binding to carcinoembryonic antigen-related cell adhesion molecule 1. Intraperitoneal infection with the murine CoV strain JHM (JHMV) induces acute mild hepatitis in mice. While both innate and acquired immune responses play a significant role in the protection against murine CoV infection in mice, CD8(+) cytotoxic T lymphocytes (CTLs) and interferon-gamma are essential for viral clearance in JHMV-induced hepatitis. In addition, CoVs are characterized by high diversity, caused by mutations, recombination, and gene gain/loss. 25V16G is an immune-escape JHMV variant, which lacks a dominant CTL epitope. By evading immune responses, 25V16G establishes persistent infections, leading to granulomatous serositis in interferon-gamma-deficient mice. These examples of CoV-associated pathogenesis in mice might provide useful information on other CoV infections, including coronavirus disease 2019 (COVID-19). Twit Text FOAVip Role of cytotoxic T lymphocytes and interferon-gamma in coronavirus infection: Lessons from murine coronavirus infections in mice ????J Vet Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=32759577 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32759577 #FOAvip English Wikipedia <ref>{{Cite pmid|32759577}}</ref> Role of cytotoxic T lymphocytes and interferon-gamma in coronavirus infection: Lessons from murine coronavirus infections in mice #MMPMID32759577 Kyuwa S; Sugiura Y J Vet Med Sci 2020[Oct]; 82 (10): 1410-1414 PMID32759577show ga Murine coronavirus (CoV) is a beta-CoV that infects mice by binding to carcinoembryonic antigen-related cell adhesion molecule 1. Intraperitoneal infection with the murine CoV strain JHM (JHMV) induces acute mild hepatitis in mice. While both innate and acquired immune responses play a significant role in the protection against murine CoV infection in mice, CD8(+) cytotoxic T lymphocytes (CTLs) and interferon-gamma are essential for viral clearance in JHMV-induced hepatitis. In addition, CoVs are characterized by high diversity, caused by mutations, recombination, and gene gain/loss. 25V16G is an immune-escape JHMV variant, which lacks a dominant CTL epitope. By evading immune responses, 25V16G establishes persistent infections, leading to granulomatous serositis in interferon-gamma-deficient mice. These examples of CoV-associated pathogenesis in mice might provide useful information on other CoV infections, including coronavirus disease 2019 (COVID-19). |Animals[MESH] |Coronavirus Infections/immunology/*veterinary/virology[MESH] |Interferon-gamma/*physiology[MESH] |Mice[MESH] |Murine hepatitis virus/*pathogenicity[MESH]Role of cytotoxic T lymphocytes and interferon-gamma in coronavirus in(epmc).pdf DeepDyve Pubget Overpricing