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10.1016/j.phrs.2020.105114 http://scihub22266oqcxt.onion/10.1016/j.phrs.2020.105114 32758635!7834389!32758635     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Res 2020 ; 161 (ä): 105114 Nephropedia Template TP {{tp|p=32758635|t=2020. COVID-19: Pharmacology and kinetics of viral clearance |pdf=|usr=}}{{32758635}} gab.com Text COVID-19: Pharmacology and kinetics of viral clearance JO: Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=32758635 #FOAvip Coronavirus Disease 2019 (COVID-19) is a pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical spectrum of COVID-19 is broad and varies from mild to severe forms complicated by acute respiratory distress and death. This heterogeneity might reflect the ability of the host immune system to interact with SARS-CoV2 or the characteristics of the virus itself in terms of loads or persistence. Information on this issue might derive from interventional studies. However, results from high-quality trials are scarce. Here we evaluate the level of evidence of available published interventional studies, with a focus on randomised controlled trials and the efficacy of therapies on clinical outcomes. Moreover, we present data on a large cohort of well-characterized patients hospitalized at a single University Hospital in Milano (Italy), correlating viral clearance with clinical and biochemical features of patients. Twit Text FOAVip COVID-19: Pharmacology and kinetics of viral clearance ????Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=32758635 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32758635 #FOAvip English Wikipedia <ref>{{Cite pmid|32758635}}</ref> COVID-19: Pharmacology and kinetics of viral clearance #MMPMID32758635 Farina N; Ramirez GA; De Lorenzo R; Di Filippo L; Conte C; Ciceri F; Manfredi AA; Rovere-Querini P Pharmacol Res 2020[Nov]; 161 (ä): 105114 PMID32758635show ga Coronavirus Disease 2019 (COVID-19) is a pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical spectrum of COVID-19 is broad and varies from mild to severe forms complicated by acute respiratory distress and death. This heterogeneity might reflect the ability of the host immune system to interact with SARS-CoV2 or the characteristics of the virus itself in terms of loads or persistence. Information on this issue might derive from interventional studies. However, results from high-quality trials are scarce. Here we evaluate the level of evidence of available published interventional studies, with a focus on randomised controlled trials and the efficacy of therapies on clinical outcomes. Moreover, we present data on a large cohort of well-characterized patients hospitalized at a single University Hospital in Milano (Italy), correlating viral clearance with clinical and biochemical features of patients. |*COVID-19 Drug Treatment[MESH] |*SARS-CoV-2[MESH] |Antiviral Agents/pharmacology/*therapeutic use[MESH] |COVID-19/*virology[MESH] |Humans[MESH]COVID-19: Pharmacology and kinetics of viral clearance (epmc).pdf DeepDyve Pubget Overpricing