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10.1016/j.lfs.2020.118202 http://scihub22266oqcxt.onion/10.1016/j.lfs.2020.118202 32758625!7397991!32758625     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Life+Sci 2020 ; 258 (ä): 118202 Nephropedia Template TP {{tp|p=32758625|t=2020. Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review |pdf=|usr=}}{{32758625}} gab.com Text Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review JO: Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32758625 #FOAvip Pandemic coronavirus disease-2019, commonly known as COVID-19 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious disease with a high mortality rate. Various comorbidities and their associated symptoms accompany SARS-CoV-2 infection. Among the various comorbidities like hypertension, cardiovascular disease and chronic obstructive pulmonary disease, diabetes considered as one of the critical comorbidity, which could affect the survival of infected patients. The severity of COVID-19 disease intensifies in patients with elevated glucose level probably via amplified pro-inflammatory cytokine response, poor innate immunity and downregulated angiotensin-converting enzyme 2. Thus, the use of ACE inhibitors or angiotensin receptor blockers could worsen the glucose level in patients suffering from novel coronavirus infection. It also observed that the direct beta-cell damage caused by virus, hypokalemia and cytokine and fetuin-A mediated increase in insulin resistance could also deteriorate the diabetic condition in COVID-19 patients. This review highlights the current scenario of coronavirus disease in pre-existing diabetic patients, epidemiology, molecular perception, investigations, treatment and management of COVID-19 disease in patients with pre-existing diabetes. Along with this, we have also discussed unexplored therapies and future perspectives for coronavirus infection. Twit Text FOAVip Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review ????Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=32758625 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32758625 #FOAvip English Wikipedia <ref>{{Cite pmid|32758625}}</ref> Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review #MMPMID32758625 Das S; K R A; Birangal SR; Nikam AN; Pandey A; Mutalik S; Joseph A Life Sci 2020[Oct]; 258 (ä): 118202 PMID32758625show ga Pandemic coronavirus disease-2019, commonly known as COVID-19 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious disease with a high mortality rate. Various comorbidities and their associated symptoms accompany SARS-CoV-2 infection. Among the various comorbidities like hypertension, cardiovascular disease and chronic obstructive pulmonary disease, diabetes considered as one of the critical comorbidity, which could affect the survival of infected patients. The severity of COVID-19 disease intensifies in patients with elevated glucose level probably via amplified pro-inflammatory cytokine response, poor innate immunity and downregulated angiotensin-converting enzyme 2. Thus, the use of ACE inhibitors or angiotensin receptor blockers could worsen the glucose level in patients suffering from novel coronavirus infection. It also observed that the direct beta-cell damage caused by virus, hypokalemia and cytokine and fetuin-A mediated increase in insulin resistance could also deteriorate the diabetic condition in COVID-19 patients. This review highlights the current scenario of coronavirus disease in pre-existing diabetic patients, epidemiology, molecular perception, investigations, treatment and management of COVID-19 disease in patients with pre-existing diabetes. Along with this, we have also discussed unexplored therapies and future perspectives for coronavirus infection. |Angiotensin-Converting Enzyme 2[MESH] |Antiviral Agents/therapeutic use[MESH] |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |Comorbidity[MESH] |Coronavirus Infections/drug therapy/*epidemiology/genetics[MESH] |Diabetes Mellitus/drug therapy/*epidemiology/genetics[MESH] |Disease Management[MESH] |Humans[MESH] |Hypoglycemic Agents/therapeutic use[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/genetics[MESH] |Pneumonia, Viral/drug therapy/*epidemiology/genetics[MESH] |Polymorphism, Genetic[MESH]Role of comorbidities like diabetes on severe acute respiratory syndro(epmc).pdf DeepDyve Pubget Overpricing